Immunomodulatory role of tumor microenvironment on oncological outcomes in advanced laryngeal cancer.

Background: The study evaluated the prognostic impact of the immune microenvironment in LSCC with markers of major immune cells to identify the key determinants of short-term disease-free survival (ST DFS) and reveal factors related to disease progression.

Methods: The study cohort included 61 patients who underwent total laryngectomy, 83.6% of whom were male with a mean age of 64.