A Low FODMAP Diet Supplemented with L-Tryptophan Reduces the Symptoms of Functional Constipation in Elderly Patients.

(1) Background: The elderly suffer from functional constipation (FC), whose causes are not fully known, but nutritional factors may play a role. The aim of the present study was to assess the effect of a low FODMAP diet supplemented with L-tryptophan (TRP) on its metabolism and symptoms of functional constipation in elderly patients. (2) Methods: This study included 40 people without abdominal complaints (Group I, controls) and 60 patients with FC, diagnosed according to the Rome IV Criteria (Group II).

The Variability of Tryptophan Metabolism in Patients with Mixed Type of Irritable Bowel Syndrome.

Patients with a mixed type of irritable bowel syndrome (IBS-M) experience constipation and diarrhea, which alternate between weeks or months. The pathogenesis of this syndrome is still little understood. The aim of the study was mainly to evaluate the urinary excretion of selected tryptophan (TRP) metabolites during the constipation and diarrhea periods of this syndrome.

The clinical value of breath ammonia determination in patients with irritable bowel syndrome.

Unlabelled: Gastrointestinal tract is the major source of ammonia (NH3). NH3 is produced by bacterial hydrolysis of urea as well as by bacterial protein deamination. The intensity of this process depends on protein intake and the amount of gut bacteria.

A Reduced Tryptophan Diet in Patients with Diarrhoea-Predominant Irritable Bowel Syndrome Improves Their Abdominal Symptoms and Their Quality of Life through Reduction of Serotonin Levels and Its Urinary Metabolites.

(1). An essential component of any treatment for patients with irritable bowel syndrome (IBS) is an adequate diet. Currently, a low FODMAP diet is recommended as a first-line therapy, but it does not relieve abdominal discomfort in all patients, and alternative nutritional treatment is required.

Altered Tryptophan Metabolism on the Kynurenine Pathway in Depressive Patients with Small Intestinal Bacterial Overgrowth.

The causes of depression are diverse and are still not fully understood. Recently, an increasing role is attributed to nutritional and inflammatory factors. The aim of this study was to evaluate selected metabolites of the tryptophan kynurenine pathway in depressive patients with small intestinal bacterial overgrowth (SIBO).

Altered tryptophan metabolism in patients with recurrent functional abdominal pain.

Unlabelled: The causes of functional abdominal pain are still unclear. The role of food factors in their pathogenesis has been assessed by many researches, but the obtained results are varied.

Aim: The aim of present study was to evaluate metabolism of tryptophan, which is substrate for serotonin synthesis and other bioactive compounds, in patients with recurrent functional abdominal pain.

The value of melatonin supplementation in postmenopausal women with Helicobacter pylori-associated dyspepsia.

Background: Dyspeptic syndrome is particularly common in postmenopausal women in the form of epigastric pain. The aim of the study was to assess the role of melatonin in chronic dyspepsia in this group of women, and examine the role of Helicobacter infection.

Methods: The study comprised 152 subjects including 30 healthy women (Group I), 60 women with asymptomatic H.

Usefulness of the hydrogen breath test in patients with functional dyspepsia.

Introduction: The pathogenesis of functional dyspepsia is complex and not well understood. Therefore, in this disease there should be considered involvement of different pathogenic factors, including intestinal bacteria.

Aim: To evaluate the results of the hydrogen breath test in relation to the clinical picture of functional dyspepsia.

[Zaburzenia czynnościowe przewodu pokarmowego u osób z przerostem bakteryjnym jelita cienkiego].

Unlabelled: Small intestinal bacterial overgrowth (SIBO) is a frequent cause of chronic abdominal complaining.

Aim: The aim of this study was to assess the prevalence of the functional disorders in this group patients.

Materials And Methods: The study was conducted in a group of 426 subjects, aged 22-65, including 294 women and 132 men with intestinal functional diseases, as defined in Rome IV Criteria.

[The number of intraepithelial lymphocytes in digestive tract in patients with IgG-dependent intolerance of cereal products].

Unlabelled: Abnormal reaction of food antigens cause a variety disorders of gastrointestinal tract. It is not clear why exactly the same products provoke diarrhea or constipation.

Aim: The aim of this study was to assess the number of intraepithelial lymphocytes (IEL) in different parts of gastrointestinal tract in patients with specific IgG antibodies against wheat and secale products.

Changes in the lipid profile of patients with asymptomatic and symptomatic helicobacter pylori infection.

Objective: Introduction: Helicobacterpylori ( H. pylori) infection often coexists with coronary artery disease, but the causal relationship is not clear as yet. The aim: to assess the lipidogram of patients with asymptomatic and symptomatic H.

The Diagnosis of Sigmoid Liposarcoma in a Young Male with Metabolic Syndrome.

The clinical picture and risk factors are decisive in differential diagnosis. It was proved that patients with metabolic syndrome have increased incidence of malignant tumours. The visceral adipose tissue releases active proteins that promote oncogenesis.