Background Medications in which the risk of adverse events exceeds the expectations of clinical benefits are called potentially inappropriate medications (PIMs). To identify the use of PIMs in elderly patients, the most commonly used tool are the Beers criteria, developed for the population of the United States. Recently, a consensus panel of Argentine experts developed the first Latin American tool, called the IFAsPIAM List.
View Article and Find Full Text PDFObjectives: To perform a list agreed by Argentinean experts and adapted to the local context containing potentially inappropriate (PI) medications in old people (OP) usingthe Delphi consensus technique optimized for this subject.
Methods: A preliminary list of potentially inappropriate medications (PIM) was drawn up based on foreign PIM lists and a selective search in the scientific literature. The iterative Delphi process was used to submit the active pharmaceutical ingredients (APIs) of the preliminary PIM list to the panel of Argentinean experts.
Rev Fac Cien Med Univ Nac Cordoba
January 2017
Background: The statistical analysis of survey responses based on a categorical Likert scale, as those used in the Delphi technique, has been questioned because the methodology used is based on numerical data analysis.
Aim: To develop criteria for defining the consensus achievement in Delphi studies conducted for the assessment of potentially inappropriate medications (PIM) in the elderly.
Methods: It was constructed an index (Yq) which takes into account the agreement by pairs of evaluators, whose calculus equation is based on combinatorial analysis.
Background: Domperidone is widely prescribed in patients with gastrointestinal disorders but some cardiac adverse effects have been recently reported.
Aim: To evaluate the risk of QT prolongation, ventricular arrhythmias and sudden cardiac death associated with the use of oral domperidone in adults without cancer.
Material And Methods: Systematic searches in MEDLINE, LILACS, SciELO, the Cochrane Library and regulatory agencies websites were performed, followed by a manual search of cited references.
Aims: To assess the association of the use of domperidone in infants with QTc interval prolongation and proarrhythmic events.
Methods: A systematic search of the scientific literature was conducted without any date or language restriction. The electronic database MEDLINE and the sources LILACS, ScIELO and Cochrane library were consulted.
Objective: To evaluate clonal dissemination of methicillin-resistant coagulase-negative staphylococci (CNS).
Setting: Neonatal intensive care unit of a 180-bed, university-affiliated general hospital.
Patients: Neonates admitted to the neonatal intensive care unit between March 1999 and October 2000, from whom CNS were isolated as a unique pathogen.