Reconstruction of deep and perforating corneal defects in dogs-A review (Part I/III): Autogenous ocular tissues, donor tissues, and corneal clarity scoring.

Corneal reconstruction is a key part of veterinary ophthalmic practice and numerous reconstructive techniques have been described for use in small animals in the peer-reviewed veterinary literature written in English. Despite the evidence accrued over the last six decades in over 40 clinical articles and numerous other publications on ocular surface health, several key areas require further study. The comparison between studies is difficult due to elements that go beyond common factors, such as the indication for surgery, the reconstructive technique preferred by the surgeon or the availability of reconstructive materials.

Follicular conjunctivitis in dogs: A retrospective study (2007-2022).

Objective: To evaluate the incidence, clinical features, treatment, and outcome of canine follicular conjunctivitis (CFC).

Procedure: Medical records of dogs diagnosed with CFC were reviewed. Data recorded included signalment, duration of clinical signs and treatment details prior to presentation, concurrent ocular/systemic diseases, ocular clinical signs, cytology, treatment, follow-up, and outcome.

Topical 1% cyclosporine eyedrops for the treatment of crystalline corneal dystrophy in dogs.

Background: Crystalline corneal dystrophy (CCD) is the most common type of corneal lipidic deposition in dogs. CCD is a primary metabolic disorder of the corneal fibroblast featuring an accumulation of extracellular and intracellular lipid deposits. Corneal lipid deposits create a corneal opacity and modify the interfibrillar collagen distance, inducing light scattering.

Diagnoses and key for the larvae of Progomphus Selys, 1854 from Argentina (Anisoptera: Gomphidae), with first larval descriptions for P. aberrans Belle, 1973 and P. kimminsi Belle, 1973.

Ten species of Progomphus Selys, 1854 are known to occur in Argentina. The larval stages of only four of them are described. We here add the larval descriptions of two species: P.

Prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus: A 10-year clinical study (2009-2019).

Background: Although ocular findings in diabetic patients are well described, prevalence data for those is unknown.

Aim: To describe the prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus.

Methods: Medical records from diabetic dogs assessed by the ophthalmology and the internal medicine services at the Veterinary Teaching Hospital of the Autonomous University of Barcelona were reviewed (2009-2019).

Urrets-Zavalia syndrome following cataract surgery in dogs: A case series.

Background: In human medicine, Urrets-Zavalia syndrome (UZS) is a well-recognized but uncommon postoperative complication characterized by a fixed dilated pupil, accompanied by iris atrophy and glaucoma. Although it was originally reported in 1963 after penetrating keratoplasty surgery for keratoconus, it has been associated with various ophthalmic procedures such as cataract surgery. The condition has not been previously published in the veterinary literature.

Safety and efficacy of unilateral topical application of rocuronium bromide in healthy scops owls (Otus scops).

Objective: To evaluate the safety and efficacy of unilateral topical application of rocuronium bromide in scops owls.

Animals Studied: Ten healthy adult scops owls.

Procedures: Birds weighting between 82-111 g were enrolled.

Intracanalicular injection of N-acetylcysteine as adjunctive treatment for sialoceles in dogs: 25 cases (2000-2017).

Objective: To describe intracanalicular injection of 10% N-acetylcysteine (IINAC) as adjunctive treatment for sialoceles in dogs.

Animals: 25 client-owned dogs.

Procedures: Hard copy medical records at 2 veterinary ophthalmology practices were searched to identify dogs that underwent IINAC for treatment of sialoceles from January 2000 to December 2017.

Effects of topical 1% cyclopentolate hydrochloride on quantitative pupillometry measurements, tear production and intraocular pressure in healthy horses.

Objective: To evaluate the effect of topical cyclopentolate hydrochloride (CH) on quantitative pupillometric readings (PR), tear production (TP), and intraocular pressure (IOP) in healthy horses.

Animals Studied: Fourteen client-owned horses.

Procedures: In a two-phase design study, each animal received 1% CH ophthalmic solution in the left eye [treated] and 0.

Feline leishmaniosis: diagnosis, treatment and outcome in 16 cats.

Objectives: Leishmaniosis is a vector-borne disease and in European countries is caused by . Cats are considered secondary reservoirs of the infection in endemic areas. The objective of this retrospective study is to describe the clinical findings, diagnosis, treatment and outcome of feline leishmaniosis (FeL) in 16 cats in Spain.

Corneoconjunctival transposition for the treatment of deep stromal to full-thickness corneal defects in dogs: A multicentric retrospective study of 100 cases (2012-2018).

Objective: To describe and evaluate the use of corneoconjunctival transposition (CTT) as a surgical treatment for canine deep stromal ulcers, descemetoceles, and full-thickness corneal defects and to determine its efficacy in preserving corneal graft transparency and vision.

Animals Studied: One hundred client-owned dogs with deep stromal ulcers, descemetoceles, or full-thickness corneal defects.

Methods: Medical records of canine patients that underwent CCT, from 2012 to 2018, were reviewed.

Cryopreservation (-20°C) of equine corneoscleral tissue: Microbiological, histological, and ultrastructural study.

Objective: To evaluate microbiological, histological, and ultrastructural characteristics of short-term cryopreserved (STC) equine corneoscleral tissue (<1 year), and to compare it with long-term cryopreserved (LTC) tissue (>7 years).

Animals Studied: Thirty-four healthy equine globes.

Procedure: After a decontamination protocol, globes were enucleated and stored at -20°C in broad-spectrum antibiotics.

A multicenter retrospective study on cryopreserved amniotic membrane transplantation for the treatment of complicated corneal ulcers in the dog.

Objective: To describe the surgical technique and outcome of amniotic membrane transplantation (AMT) for treatment of complicated corneal ulcers in dogs.

Animals Studied: One hundred and eleven dogs.

Procedure: Medical records (2010-2017) were reviewed to identify canine patients that underwent AMT for the treatment of complicated corneal ulcers.

Ophthalmologic findings associated with Rhodococcus equi bronchopneumonia in foals.

Objective: To describe ocular findings associated with Rhodococcus equi bronchopneumonia in foals, and to determine whether severity of the ocular lesions is related with outcome.

Animals Studied: Foals diagnosed with R equi infection at the VTH-UAB from January 2002 to December 2017.

Procedure: Rhodococcus equi infection was diagnosed by means of clinical signs, radiographic/ultrasonographic findings, and/or positive culture.

Corneal thickness, endothelial cell density, and morphological and morphometric features of corneal endothelial cells in goats.

OBJECTIVE To determine corneal thickness (CT), endothelial cell density (ECD), and morphological and morphometric features of caprine eyes and to assess effects of aging on these variables. SAMPLE 27 healthy eyes of 19 Murciano-Granadina goats. PROCEDURES Goats were classified into 2 age groups (kids, 14 months old [14 eyes]; and adults, 7 to 10 years old [13 eyes]).

Endothelial cell density and characterization of corneal endothelial cells in the Tawny Owl (Strix aluco) using specular microscopy.

Objective: To determine endothelial cell density (ECD) and morphology and morphometry of corneal endothelial cells in the tawny owl (Strix aluco), as well as to report the effects of aging on these parameters.

Animal Study And Procedures: Twenty tawny owls were included in the study and classified into 2 groups according to their age: fledglings (<1 year old) and adults (>1 year old). Central corneal endothelium was studied by means of noncontact specular microscopy (Specular Microscope SP-2000P; Topcon, Tokyo, Japan), and results for ECD (cells/mm ), mean cell area ((MCA (μm )), polymegathism (CV), and pleomorphism (% hexagonal cells) were obtained.

A dose-escalation ex vivo study on the effects of intracameral benzalkonium chloride in rabbits.

Background: Rabbits are currently not a good model for studying diseases of the corneal endothelium because their corneal endothelial cells (CECs) maintain a high proliferative capacity throughout almost all their life. Addressing this particular feature might allow the use of this species for such a purpose. The aim of this study was to evaluate the corneal endothelial injury after intracameral benzalkonium chloride (BAC) injection into rabbit eyes ex vivo, and to establish the most suitable starting dose for an in vivo study aimed at developing an animal model of corneal endothelial disease.

Cryopreservation (-20 °C) of canine corneoscleral tissue: histological, microbiological, and ultrastructural study.

Objective: To evaluate microbiological, histological, and ultrastructural characteristics of short-term cryopreserved (STC) canine corneoscleral tissue (<1 year) and to compare it with long-term cryopreserved (LTC) tissue (>6 years).

Animals Studied: Thirty-six healthy canine globes.

Procedure: After a decontamination protocol, globes were enucleated and stored at -20 °C.

Modified brow suspension technique for the treatment of pseudoptosis due to redundant frontal skin in the dog: a retrospective study of 25 cases.

Purpose: To describe the outcome of modified brow suspension technique for the treatment of upper eyelid pseudoptosis in canine patients with redundant frontal skin folds.

Methods: Medical records from 1999 to 2015 were retrospectively reviewed. Only dogs that underwent modified brow suspension for treating bilateral pseudoptosis were included in the study.

Effect of topical 1% cyclopentolate hydrochloride on tear production, pupil size, and intraocular pressure in healthy Beagles.

Objective: The objective of the study was to evaluate the effect of topical 1% cyclopentolate hydrochloride (CH) on tear production (TP), pupil size (PS), and intraocular pressure (IOP) in dogs.

Animal Studied: Fifteen healthy beagle dogs from the UAB research-teaching colony.

Procedure: Dogs without ocular diseases were included.

A Swine Model of Selective Geographic Atrophy of Outer Retinal Layers Mimicking Atrophic AMD: A Phase I Escalating Dose of Subretinal Sodium Iodate.

Purpose: To establish the dose of subretinal sodium iodate (NaIO3) in order to create a toxin-induced large animal model of selective circumscribed atrophy of outer retinal layers, the retinal pigment epithelium (RPE), and photoreceptors, by spectral-domain optical coherence tomography (SD-OCT) and immunocytochemistry.

Methods: Fifteen male and female healthy Yorkshire pigs received unilateral subretinal escalating doses of NaIO3 under general anesthesia. In all the animals, volumes of 0.

Cryopreservation (-20 °C) of feline corneoscleral tissue: histologic, microbiologic, and ultrastructural study.

Objective: To evaluate microbiological, histologic, and ultrastructural characteristics of short-term cryopreserved (STC) feline corneoscleral tissue (<1 year) and to compare it with long-term cryopreserved (LTC) tissue (>7 years).

Animals Studied: Twenty healthy feline globes were obtained from 2003 to 2013.

Procedure: After a decontamination protocol, globes were enucleated and stored at -20 °C in broad-spectrum antibiotics.

Corneal grafting for the treatment of full-thickness corneal defects in dogs: a review of 50 cases.

Objective: To describe corneal grafting for the treatment of full-thickness corneal defects in dogs and to determine its effectiveness in preserving vision.

Methods: A review of the medical records of dogs that underwent corneal grafting following corneal perforations (≥3 mm) at the VTH-UAB from 2002 to 2012 was carried out.

Results: Fifty dogs of different breed, age and gender were included.

Effects of age and breed on corneal thickness, density, and morphology of corneal endothelial cells in enucleated sheep eyes.

Objective: The purpose of the study was to determine corneal thickness (CT), endothelial cell density (ECD), morphology, and morphometry in ovine eyes, and to report the effects of age and breed on these parameters.

Animals Studied And Procedures: Forty-eight healthy ovine eyes were classified into six groups (eight eyes per group) according to animals' age (lambs and adults) and breed (Manchega, Ripollesa, and Rasa Aragonesa). Endothelial cell density (cells/mm(2) ) and CT (μm) were calculated in the central cornea and four peripheral quadrants by means of specular microscopy.