Publications by authors named "Marta Gonzalez-Sierra"
The monocytes to high-density lipoprotein (HDL)-cholesterol ratio (MHR) indicates inflammation based on the anti-inflammatory properties of HDL-cholesterol as well as the pro-inflammatory effect of monocytes. Several studies have investigated MHR in various disorders, specifically in cardiovascular diseases. Consequently, MHR has been significantly associated with cardiovascular and all-cause mortality in the general population, regardless of established risk factors.
View Article and Find Full Text PDFRed cell distribution width (RDW) is a measure of the variation in mean corpuscular volume that reflects the degree of anisocytosis on the peripheral blood smear. RDW value variation has been implicated in several disorders including chronic inflammatory processes and cardiovascular (CV) diseases. In the present work, our objective was to study the relationship that RDW has with the characteristics of the disease in patients with rheumatoid arthritis (RA), focusing on CV risk factors and subclinical atherosclerosis.
View Article and Find Full Text PDFMean Platelet Volume in a Series of 315 Patients with Rheumatoid Arthritis: Relationship with Disease Characteristics, including Subclinical Atherosclerosis and Cardiovascular Comorbidity.
Diagnostics (Basel)
October 2023
Article Synopsis
- Mean platelet volume (MPV) is a measure of the average size of platelets and is linked to various health disorders, including rheumatoid arthritis (RA).
- A study involving 315 RA patients and 208 control subjects found that RA patients had lower MPV levels compared to controls, suggesting a significant negative relationship between MPV and disease activity.
- The research indicated that MPV was not associated with cardiovascular risk factors or lipid profiles, but was inversely correlated with inflammatory markers like erythrocyte sedimentation rate and interleukin-6.
The neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammatory index (SIRI, neutrophils × monocytes/lymphocytes) have been described as potential blood-derived inflammatory biomarkers in several diseases. Rheumatoid arthritis is an inflammatory disease that has been related to an increased risk of cardiovascular (CV) disease. In the present work, we analyze how these hematological composite scores of inflammation are related to classic CV risk factors and subclinical atherosclerosis in patients with RA.
View Article and Find Full Text PDFInvasive Physiotherapy as a Treatment of Spasticity: A Systematic Review.
Degener Neurol Neuromuscul Dis
March 2022
Introduction: Nowadays, a set of novel physiotherapy techniques have emerged, in which the physical agent used to try to reduce spasticity is applied percutaneously, specifically, through the patient's skin. The aim of this work is to encompass all the invasive techniques used in spasticity in a single article, updating the existing bibliography.
Methodology: A systematic review was carried out between December 2020 and April 2021 in the Web of Science, Scopus and PubMed databases, selecting the clinical trials that used acupuncture, electroacupuncture or dry needling as a treatment for spasticity.