Restoration of grasping in an upper limb amputee using the myokinetic prosthesis with implanted magnets.

The loss of a hand disrupts the sophisticated neural pathways between the brain and the hand, severely affecting the level of independence of the patient and the ability to carry out daily work and social activities. Recent years have witnessed a rapid evolution of surgical techniques and technologies aimed at restoring dexterous motor functions akin to those of the human hand through bionic solutions, mainly relying on probing of electrical signals from the residual nerves and muscles. Here, we report the clinical implementation of an interface aimed at achieving this goal by exploiting muscle deformation, sensed through passive magnetic implants: the myokinetic interface.

Transcutaneous Magnet Localizer for a Self-Contained Myokinetic Prosthetic Hand.

Objective: The search for a physiologically appropriate interface for the control of dexterous hand prostheses is an ongoing challenge in bioengineering. In this context, we proposed an interface, named myokinetic control interface, based on the localization of magnets implanted in the residual limb muscles, to monitor their contractions and send appropriate commands to the artificial hand. As part of such concept, this interface requires a transcutaneous magnet localizer that can be integrated in a self-contained limb prosthesis, a feature yet to be realized within the current state of the art.

To What Extent Implanting Single vs Pairs of Magnets Per Muscle Affect the Localization Accuracy of the Myokinetic Control Interface? Evidence From a Simulated Environment.

Objective: We recently proposed a new concept of human-machine interface to control hand prostheses which we dubbed the myokinetic control interface. Such interface detects muscle displacement during contraction by localizing permanent magnets implanted in the residual muscles. So far, we evaluated the feasibility of implanting one magnet per muscle and monitoring its displacement relative to its initial position.

Optimal Spatial Sensor Design for Magnetic Tracking in a Myokinetic Control Interface.

Background And Objectives: Magnetic tracking involves the use of magnetic sensors to localize one or more magnetic objectives, in those applications in which a free line-of-sight between them and the operator is hampered. We applied this concept to prosthetic hands, which could be controlled by tracking permanent magnets implanted in the forearm muscles of amputees (the myokinetic control interface). Concerning the system design, the definition of a sensor distribution which maximizes the information, while minimizing the computational cost of localization, is still an open problem.

Localization accuracy of multiple magnets in a myokinetic control interface.

Magnetic localizers have been widely investigated in the biomedical field, especially for intra-body applications, because they don't require a free line-of-sight between the implanted magnets and the magnetic field sensors. However, while researchers have focused on narrow and specific aspects of the localization problem, no one has comprehensively searched for general design rules for accurately localizing multiple magnetic objectives. In this study, we sought to systematically analyse the effects of remanent magnetization, number of sensors, and geometrical configuration (i.

The Myokinetic Control Interface: How Many Magnets Can be Implanted in an Amputated Forearm? Evidence From a Simulated Environment.

We recently introduced the concept of a new human-machine interface (the myokinetic control interface) to control hand prostheses. The interface tracks muscle contractions via permanent magnets implanted in the muscles and magnetic field sensors hosted in the prosthetic socket. Previously we showed the feasibility of localizing several magnets in non-realistic workspaces.

Catheter segmentation in X-ray fluoroscopy using synthetic data and transfer learning with light U-nets.

Background and objectivesAutomated segmentation and tracking of surgical instruments and catheters under X-ray fluoroscopy hold the potential for enhanced image guidance in catheter-based endovascular procedures. This article presents a novel method for real-time segmentation of catheters and guidewires in 2d X-ray images. We employ Convolutional Neural Networks (CNNs) and propose a transfer learning approach, using synthetic fluoroscopic images, to develop a lightweight version of the U-Net architecture.

Development of an Embedded Myokinetic Prosthetic Hand Controller.

The quest for an intuitive and physiologically appropriate human machine interface for the control of dexterous prostheses is far from being completed. In the last decade, much effort has been dedicated to explore innovative control strategies based on the electrical signals generated by the muscles during contraction. In contrast, a novel approach, dubbed myokinetic interface, derives the control signals from the localization of multiple magnetic markers (MMs) directly implanted into the residual muscles of the amputee.