Publications by authors named "Marta Garcia-Valdivia"
Article Synopsis
- Bioengineered autologous skin substitutes (BASS) are being researched for enhancing skin burn therapy, but more studies are needed on their effectiveness and optimization.
- The study focused on testing various antiseptics (like sodium hypochlorite and chlorhexidine) on BASS to assess their impact on cell viability, inflammation, and skin barrier integrity.
- Sodium hypochlorite emerged as the most effective antiseptic, maintaining high cell viability and a favorable cytokine response, making it a promising option for post-transplantation wound care in BASS.
In recent years, new therapies, such as skin cell lines injections, have emerged to promote re-epithelialization of damaged areas such as chronic ulcers or to treat patients with severe burns. Antiseptics are commonly used during wound clinical management to avoid serious infections, but they may delay the healing process due to their apparent cytotoxicity to skin cells. The cytotoxicity of ethanol, chlorhexidine digluconate, sodium hypochlorite, povidone iodine and polyhexanide was evaluated in this in vitro study on human fibroblasts and keratinocytes.
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