HmbC, a Protein of the HMG Family, Participates in the Regulation of Carotenoid Biosynthesis in .

In the fungus , carotenoid production is up-regulated by light and down-regulated by the CarS RING finger protein, which modulates the mRNA levels of carotenoid pathway genes ( genes). To identify new potential regulators of genes, we used a biotin-mediated pull-down procedure to detect proteins capable of binding to their promoters. We focused our attention on one of the proteins found in the screening, belonging to the High-Mobility Group (HMG) family that was named HmbC.