Small non-coding RNAs (sncRNAs), particularly microRNAs (miRNAs), play an important role in transcriptome regulation by binding to mRNAs and post-transcriptionally inhibiting protein production. This regulation occurs in both physiological and pathological conditions, where the expression of many miRNAs is altered. Previous reports by our group and others have demonstrated that miRNA expression is also altered during aging.
View Article and Find Full Text PDFThe hippocampus is a brain area linked to cognition. The mechanisms that maintain cognitive activity in humans are poorly understood. Centenarians display extreme longevity which is generally accompanied by better quality of life, lower cognitive impairment, and reduced incidence of pathologies including neurodegenerative diseases.
View Article and Find Full Text PDFFolate-mediated one-carbon metabolism (FOCM) plays an important role in colorectal carcinogenesis. Previous studies have assessed the role of folate-mediated one-carbon metabolism (FOCM)-related gene-diet interaction in the aetiology of colorectal cancer (CRC), however, the results remained inconclusive. Thus, this study aimed to investigate dietary factors and genetic variants related to FOCM, as well as potential nutrient-gene and nutrient-lifestyle interactions, on CRC risk.
View Article and Find Full Text PDF(1) Background: Food insecurity (FI) among university students has received less attention in Europe than in other regions before and during the COVID-19 pandemic. (2) Methods: A cross-sectional study was conducted between January and March 2022 using an online questionnaire ( = 924). The questionnaire addressed food security status; demographic, socioeconomic, and educational variables; academic performance; food consumption; and social support networks.
View Article and Find Full Text PDFTo date, there are no studies that have compared university food environments (FEs) with different sociocultural contexts. Therefore, we analyzed differences in the availability and properties of commercially produced foods, in a northern and a southern European university (located in Norway and Spain, respectively). A cross-sectional observational study was conducted at OsloMet-Oslo Metropolitan University and at the University of the Basque Country UPV/EHU.
View Article and Find Full Text PDFThis study aimed to assess the prevalence and associated factors of food insecurity (FI) among university students in Germany during the COVID-19 pandemic. We conducted a cross-sectional study ( = 626) between November and December 2021 at the Justus Liebig University in Giessen, Germany, using an online questionnaire. The analysis of FI was based on the Food Insecurity Experience Scale (FIES) by the Food and Agriculture Organization (FAO).
View Article and Find Full Text PDFPurpose: Epidemiologic evidence for the association between methyl-donor nutrient intake and colorectal cancer (CRC) risk remains inconclusive. We aimed to examine the relationship between intake of vitamins of the B group, methionine, total choline and betaine and CRC risk, in a population from the CRC screening programme in the Basque Country.
Design: This observational study included 308 patients with CRC and 308 age- and sex-matched subjects as controls.
Research related to food insecurity (FI) among European university student populations is currently limited, especially the studies carried out during the COVID-19 pandemic. The present study aimed to assess the prevalence and identify possible predictors of FI among students from a Spanish public university, the University of the Basque Country UPV/EHU, during the COVID-19 pandemic. A cross-sectional observational study design was used, in which a total of 422 students completed an online survey.
View Article and Find Full Text PDFBackground: Dietary methyl donors might influence DNA methylation during carcinogenesis of colorectal cancer (CRC). However, whether the influence of methyl donor intake is modified by polymorphisms in such epigenetic regulators is still unclear.
Aim: To improve the current understanding of the molecular basis of CRC
Methods: A literature search in the Medline database, (https:// www.
There is limited evidence to support the relationship between the consumption of animal-source foods other than red meat and processed meat and colorectal cancer (CRC) risk. We aimed to examine the recent available evidence from observational studies about the association between these food groups’ intake and CRC risk. For this systematic review, we searched the PubMed database for the last five years.
View Article and Find Full Text PDFObjective: The aim of this study was to investigate food purchasing behaviors, choice determinants, and opinions about on-campus food availability by a university community and to analyze differences in these aspects between students, education and/or research staff (ERS), and administrative and services staff (ASS), and between males and females.
Methods: This was a cross-sectional study that involved a representative sample of students (n = 1089), ERS (n = 396), and ASS (n = 300) who completed an anonymous online survey. A previously adapted version of the questionnaire was administered.
Int J Environ Res Public Health
June 2021
Background: Given the lack of data about the nutritional value and other determinants of the consumption of foods and drinks sold in vending machines in European universities and the relevance of this sector in Spain, it is necessary to obtain scientific data on this topic. The present study aimed to assess the availability, nutritional profile and processing level of food products from vending machines at a Spanish public university and to investigate differences in nutritional profile according to the cost and promotion.
Methods: Cross-sectional descriptive study.
Objective: To assess the food environment at OsloMet, through the nutritional profile and processing level of available commercial foods and drinks, as well as to determine food-purchasing behaviours, preferences and opinions on the food environment, in order to identify whether interventions on campus need to be conducted.
Design: Cross-sectional descriptive study.
Setting: Pilestredet and Kjeller campus of OsloMet (Norway).
Objective: To evaluate diets in terms of nutritional characteristics and quality from the perspectives of health, greenhouse gas emissions (GHGE) and possible associations with each other in a representative sample of students at a public university.
Design: Cross-sectional. Dietary intake was evaluated with a validated FFQ, and diet quality was assessed through the Healthy Eating Index (HEI-2010) and MedDietScore (MDS).
This paper investigates the prevalence and interaction of overweight/obesity-related lifestyles (specifically, examining whether subjects meet the recommended criteria), in a representative sample of university students. This study is part of the project EHU12/24, an observational cross-sectional study, designed to assess the prevalence of excess body fat (BF) and major risk of developing overweight/obesity, according to a standardised protocol. In a cohort of 603 students, aged between 18 and 28 years, of the University of the Basque Country, information about meal patterns, diet quality, physical activity, sitting time, sleeping time, toxic habits and anthropometric measurements were collected.
View Article and Find Full Text PDFBackground: The results obtained to date concerning food groups, diet quality and colorectal cancer (CRC) risk vary according to criteria used and the study populations.
Aim: To study the relationships between food groups, diet quality and CRC risk, in an adult population of the Basque Country (North of Spain).
Methods: This observational study included 308 patients diagnosed with CRC and 308 age- and sex-matched subjects as controls.
Epidemiologic studies have revealed inconsistent evidence of gene-diet interaction in relation to colorectal cancer (CRC). The aim of this study was to analyze them in a sample of cases and controls from the population-based bowel cancer screening program of the Osakidetza/Basque Health Service. This study analyzed dietetic, genetic, demographic, socioeconomic factors and lifestyles.
View Article and Find Full Text PDFGiven the significant population diversity in genetic variation, we aimed to investigate whether single nucleotide polymorphisms (SNPs) previously identified in studies of colorectal cancer (CRC) susceptibility were also relevant to the population of the Basque Country (North of Spain). We genotyped 230 CRC cases and 230 healthy controls for 48 previously reported CRC-susceptibility SNPs. Only the rs6687758 in DUPS10 exhibited a statistically significant association with CRC risk based on the crude analysis.
View Article and Find Full Text PDFRecent evidence has shown that an unhealthy diet is associated with a higher risk of tumor recurrence, metastasis, and death among patients with colorectal cancer (CRC). The aims of this study were to assess nutritional adequacy and diet quality in a group of CRC patients postsurgery and to identify possible associations between dietary and nutritional aspects and environmental factors and weight status. This was an observational study conducted on a random sample of 74 patients, aged 50-69 years.
View Article and Find Full Text PDFIntroduction: In Western populations fish consumption is lower than meat consumption and this fact can influence on the total diet quality.
Objective: Verify if the relationship between the ratio of fish to meat consumption and diet adequacy and quality in a group of women university students.
Participants And Methods: 47 women of the University of the Basque Country (UPV/EHU) took part in this study; the mean age was 19.
Introduction: University students generally have low levels of physical activity, which could affect the body weight and composition and the knowledge and acceptance of their own body.
Objective: To assess weight status and body composition, as well as self-perception and satisfaction with body weight in university students, and to analyze the influence of sport practice and physical exercise on these variables.
Methods: A sample of 62 male students with a mean age of 20.
Studies have reported a negative association between dairy product consumption and weight status. However, not as much research has focused on cheese; therefore, the aim of this study was to study the association between cheese intake and overweight and obesity in a representative Basque adult population. A food frequency questionnaire (FFQ) was obtained from a random sample of 1081 adults (530 males and 551 females, 17-96 years old).
View Article and Find Full Text PDFThe aim of this study was to analyze the body weight satisfaction and the diet quality in a group of female university students and to assess the differences between degrees in different fields of knowledge. Participants were 47 women volunteers classified as normal weight, 29 from the degree in Human Nutrition and Dietetics and 18 from the degree in Social Work. Dietary intake was evaluated by a validated food frequency questionnaire.
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