Publications by authors named "Marshall Lawler"
Introduction: Oral mucositis (OM) is a major dose-limiting side effect of chemotherapy and radiation used in cancer treatment. Due to the complex nature of OM, currently available drug-based treatments are of limited efficacy.
Objectives: Our objectives were (i) to determine genes and molecular pathways associated with OM and wound healing using computational tools and publicly available data and (ii) to identify drugs formulated for topical use targeting the relevant OM molecular pathways.
Article Synopsis
- The study compares speech perception, a common measure for cochlear implant (CI) users, with a newly developed test called the spectral-temporally modulated ripple test (SMRT) to evaluate its effectiveness across different types of CI users.
- A total of 25 participants, including those with unilateral, bilateral CIs, and bimodal setups, were tested on both the AzBio sentence test and the SMRT, revealing a significant correlation between their performances on both assessments.
- The findings suggest that SMRT can be a reliable predictor of speech recognition abilities in noisy environments among experienced CI users, prompting the need for future studies to enhance participant diversity and explore additional applications of the SMRT.