Practice Patterns and Perspectives of the Off-Label Use of GLP-1 Agonists for Cosmetic Weight Loss.

Background: The off-label use of glucagon-like peptide 1 (GLP-1) agonists for cosmetic weight loss has captured the interest of the public. However, there is a paucity of published data on their utilization, implications, and management, particularly in the plastic surgery community.

Objectives: This study aims to explore the current practice patterns of aesthetic plastic surgeons regarding the off-label implementation of GLP-1 agonists.

Public Interest in the Off-Label Use of Glucagon-like Peptide 1 Agonists (Ozempic) for Cosmetic Weight Loss: A Google Trends Analysis.

Glucagon-like peptide 1 (GLP-1) agonists are a drug class used for the treatment of diabetes that have recently gained FDA approval for medical management of obesity. The off-label use of Ozempic (Novo Nordisk, Bagsværd, Denmark), the brand name of the GLP-1 agonist semaglutide, for cosmetic weight loss has been popularized by social media and celebrity influence. The aim of this study was to analyze with Google Trends (Alphabet Inc.

The Aging trial: Design of a randomized controlled trial to increase physical activity in middle-aged and older adults.

Background: Negative views of aging (NVOA), low self-efficacy beliefs, and poor goal planning skills represent risk factors that undermine adults' motivation to engage in physical activity (PA). Targeting these three risk factors may motivate adults to become physically active.

Objective: To assess the efficacy of Aging, a 4-week educational program that explicitly targets NVOA, low self-efficacy beliefs, and poor goal planning skills compared to a 4-week health education program.

Clinical and professional role development among experienced pediatric nurses: the pediatric medical nursing certificate program.

Issues And Purpose: The development of a multiunit-based certificate program to promote retention by increasing experienced pediatric nurses' knowledge, skills, and professional role development through a blend of didactic, clinical, and mentoring components.

Conclusions: The certificate group demonstrated an increase in knowledge and skill, advanced leadership role acquisition, promotion, certification, and graduate school matriculation, and achieved a 95% retention rate within the organization.

Practice Implications: With support from management and multidisciplinary team members, a certificate program like this can be implemented in a variety of settings and specialties.

Biocompatibility: the latest developments.

The standards for biological evaluation of medical devices are currently being evaluated. This article presents the rationale behind the current ISO 10993 series and discusses the work in progress to revise elements of the standards and to incorporate new areas. Particular issues being addressed include a new definition of biocompatibility, and quality of health, which will include product risk assessment and surveillance in the market place.

Postural organization in patients with hereditary motor and sensory neuropathy.

The postural organization in patients with hereditary motor and sensory neuropathy (HMSN) type I or II was studied clinically by means of a force platform. Balance was registered in 14 barefooted HMSN patients and healthy matched control subjects during quiet stance. The effect of visual deprivation was tested to determine the degree of visual dependency.