Serum androgen levels after streptozotocin administration in the male rat.

Serum levels of testosterone and dihydrotestosterone were measured in control and diabetic animals 5, 10 and 15 days after streptozotocin administration. The diabetic state produced a marked reduction in serum androgen levels 10 and 15 days after streptozotocin administration. Insulin treatment partially restored the circulating androgen levels when administered to diabetic rats.