Old World cutaneous leishmaniasis: diagnosis and treatment.

Cutaneous leishmaniasis is a major world health problem. Diagnosis is suspected on evocative clinical presentation in patients living in or coming from endemic areas. Several methods have been used.

Cowden syndrome.

Background: Cowden syndrome is a rare genodermatosis charactarized by presence of multiple hamartomas. The aim of the study was to specify the clinical, therapeutic and prognostic aspects of Cowden syndrome.

Cases Report: Our study included 4 patients with Cowden syndrome, 2 males and 2 females between 14 and 46 years old.

Childhood dermatomycoses study in Sfax Hospital, Tunisia.

Mycoses are frequent affections in childhood. Fungal type varies according to the age and the affected organ. The aim of this study was to determine the aetiological agents of childhood dermatomycoses and to draw attention to the diversity of their clinical manifestations.

[Epidemiologic, clinic and allergologic profile of atopic dermatitis in south Tunisia].

Background: Atopic dermatitis (AD) is the collection of the cutaneous inflammatory manifestations which are chronic or repetitive associated with the other atopic diseases. The prevalence of the AD varies from one country to another.

Aim: The aims of this work in to study the allergolicol, clinical and epidemiological profile of the AD in the south of Tunisia.

HLA- A, B, DR and DQ alleles study in Tunisian patients with atopic dermatitis.

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease resulting from the interaction between envirommental and genetic factors. Many genes are involved in the etiopathology of AD, such as HLA genes.

Objectives: Study the association between HLA-A, B, DR and DQ genes and the AD.

[Childhood actinic lichen planus (6 cases)].

Introduction: Actinic lichen planus (ALP) is a chronic and benign disease that affects young people of the Middle East and Maghreb countries.

Purpose: To analyse clinical features and prognosis of ALP in children.

Patients And Methods: A retrospective, descriptive study of cases observed in the department of dermatology of Sfax hospital over a period of 11 years (1995-2005).

[Sexual dysfunction after colostomy].

Background: Sexual disturbances after colostomy are various. However, they probably remain underestimated in societies where sexuality is still a taboo issue. THE AIM of this prospective study was to evaluate the possible sexual behaviour and the post operative sexual disturbances in patients whome underwent colostomy.

[Epidemio-clinical profile of skin cancer in southern Tunisia].

Background: Skin cancer (SK) frequency is increasing all over the world.

Aim: We report a clinical and epidemiological study of SK in the south of Tunisia through a 1476 cases series.

Method: On the basis of a retrospective study, we report the clinical and epidemiological data collected from files of patients with skin cancers seen during a 24-year-period (1979-2002).

[Discoid lupus erythematosus with eyelid involvement. A series of nine patients].

Introduction: Discoid lupus erythematosus (DLE) is a chronic autoimmune skin disease that usually affects the sun-exposed skin. Palpebral involvement occurs uncommonly.

Material And Method: The goal of our study was to present the clinical and therapeutic features of a series of nine patients with discoid lupus erythematosus with eyelid involvement.

[Clinical polymorphism of cutaneous leishmaniasis in centre and south of Tunisia].

The cutaneous leishmaniasis (CL) is an affection which is quite well known in Tunisia. The zoonotic cutaneous leishmaniasis caused by Leishmania major by far the more frequent, is endemo-epidemic in the centre and south of the country. It is characterized by clinical polymorphism.

[Tricho-epithelioma multiplex: two cases reports].

Tricho-epitheliomas are benign tumors of the pilosebaccous apparatus. Multiple tricho-epithelioma form is particular. We report 2 new cases.

[Profile of basal cell carcinomas of the scalp after radiotherapy for tinea capitis (about 63 cases)].

The induction of basal cell carcinoma (BCC) of the scalp by X-ray therapy for tinea capitis is well known. The aim of the study was to specify the epidemiological, clinical and histological characteristics of this disease. In a retrospective study, we collected data from the files of 63 patients, with a history of radiotherapy for tinea capitis, followed between January 1995 and December 2004.

[Subacute cutaneous lupus erythematosus in childhood: a case report].

Subacute cutaneous lupus erythematosus is extremely rare in childhood. We report the case of a 7 year-old girl who presented annular erythematous infiltrated lesions on sun exposed areas since the age of 2 months. Histopathologic examination showed orthohyperkeratosis, epidermal atrophy, widespread hydropic degeneration of epidermal basal cell layer, and a dermal lymphohistiocytic infiltrate.

[Biermer disease disclosed by mucous ulcerations].

Pernicious anemia rarely induces mucous membranes lesions, wich, exceptionally reveal the disease. We report a case of a 64-year-old man who presented a clinical history of recurrent painful ulcerations of the buccal, genital and ocular muosa. He also had peripheral sensory nerve impairement of the legs.

[Necrobiosis lipoidica - 3 case reports].

Necrobiosis lipoidica is a rare degenerative disease mostly seen on the legs. The association to diabetes mellitus is usual. We report three patients with necrobiosis lipoidica located on the extremities, 2 of them were already treated for diabetes.

[Beneficial effects of antimalarials in the treatment of generalized granuloma annular in children].

Granulma annulare is a polymorphic granulomatous disease of the skin. It has a chronic course and affects mainly children and young adults. We report two cases of generalized granuloma annulare in children successfully treated with antimalarials.

Erysipelas after breast cancer treatment (26 cases).

Erysipelas is a bacterial hypodermal cellulitis usually associated with Streptococcal infection. Erysipelas of the upper limbs in women treated for breast cancer is relatively rare. We undertook a 10-year retrospective study identifying 26 cases of erysipelas of the upper limb following treatment for breast cancer; we describe the clinical, therapeutic, and evolutionary aspects.

[Radiotherapy-induced pemphigus: a case report].

A 61-year-old male patient suffering from squamous cell carcinoma of the lower lip developed pemphigus vulgaris two months after exposure to radiotherapy. Skin lesions were initially localised to the face and neck and later extended over other skin areas. The eruption are improved with glucosteroid therapy, which were stopped after six months.

[Basal cell carcinoma of the scalp after radiation therapy for tinea capitis: 33 patients].

Occurrence of basal cell carcinoma (BCC) following radiotherapy for tinea capitis is well known. The aim of this study was to specify the clinical and histological features of these BCC seen in 33 patients (1995-2000). Twenty seven men and six women were diagnosed with BCC.

[Squamous cell carcinoma complicating an hereditary epidermolysis bullosa].

The dystrophic form of hereditary epidermolysis bullosa is associated with an increased frequency of squamous cell carcinoma. We report a new case. An 18-year-old patient, carrying a Hallopeau Siemens hereditary epidermolysis bullosa, presented a subcutaneous nodular lesion, for 1 year that ulcerated and budded with inguinal lymphadenopathy.