A reliability generalization meta-analysis of the internal consistency and test-retest reliability of the pre-sleep arousal scale (PSAS).

Purpose: The Pre-Sleep Arousal Scale (PSAS) is a self-report tool for assessing cognitive and somatic arousal before sleep. While the English version is well-validated, research on translations is limited. This meta-analysis examines PSAS translations' internal consistency and reliability.

Xylan from Dinizia excelsa: Chemical characterization and biological activities.

Dinizia Excelsa is an Amazonian tree with a wide range of applications as a raw material in the industry. The objective of this study was to extract, characterize, and evaluate the biological activities of xylan extracted from Dinizia excelsa wood. The xylan was obtained in five stages, including delignification, precipitation, purification, and freeze-drying.

High-loaded tidal flow constructed wetlands coupled with microbial fuel cells: effects of the vegetation and filling material size.

The sanitation resource recovery is a contemporary strategy fully in line with the concept of the circular economy. The by-products from constructed wetlands technology include treated water, nutrients, biomass and energy. The aim of the present study was to evaluate the sewage treatment and resources recovery in constructed wetlands operating in a tidal flow configuration, coupled with microbial fuel cells (MFC).

EMBL's European Bioinformatics Institute (EMBL-EBI) in 2024.

The European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) is one of the world's leading sources of public biomolecular data. Based at the Wellcome Genome Campus in Hinxton, UK, EMBL-EBI is one of six sites of the European Molecular Biology Laboratory, Europe's only intergovernmental life sciences organization. This overview summarizes the latest developments in services that EMBL-EBI data resources provide to scientific communities globally (https://www.

Phosphoproteomics: Advances in Research on Cadmium-Exposed Plants.

With the increasing concern on heavy metal contamination in agriculture and other environmental settings, unraveling the mechanisms of cadmium (Cd) tolerance and response in plants has become highly important. Ongoing plant Cd research over the years has focused on strategic and relevant aspects, including molecular, biochemical, and physiological processes. From this perspective, phosphoproteomics appears to be an innovative and powerful approach to investigating plant responses to Cd stress.

Effects of 12 and 24 Weeks of Interdisciplinary Interventions on Health-Related Physical Fitness, Biochemical Markers, and Level of Food Processing in Overweight or Obese Adolescents: A Longitudinal Study.

Background: The aim was to investigate the effects of 12 and 24 weeks of interdisciplinary interventions on health-related physical fitness, biochemical markers, and food processing levels in overweight or obese adolescents.

Methods: Thirty-one adolescents completed 24 weeks of nutritional, psychoeducational, and physical activity interventions in addition to assessments and tests carried out before, at 12 weeks, and after 24 weeks.

Results: There were increases in lean mass ( = 0.

Parental Stress in Autistic Children with Poor Oral Hygiene: A Pilot Study to Develop and Validate a Measurement Scale.

Research indicates that children with autism spectrum disorder (ASD) exhibit a deficiency in skills and initiative when it comes to adhering to daily oral hygiene routines. This, in turn, increases the likelihood of oral pathologies, thereby placing a significant emotional strain on their parents. In addition to the typical stress they already experience, parents of children with ASD are also burdened with pediatric oral health issues.

Primary Stability of Zirconia Dental Implants with Cylindrical and Tapered Designs Across Varying Bone Densities: An In Vitro Evaluation.

While titanium implants are widely recognized for their clinical success, zirconia implants have emerged as a metal-free alternative. This study aimed to evaluate the influence of zirconia implant macrogeometry and bone density on primary implant stability. Two types of zirconia implants were tested-the Neodent Zi Ceramic Implant and the Straumann PURE Ceramic Implant, that were placed into polyurethane foam blocks mimicking different bone densities (10 PCF, 15 PCF, 20 PCF, 30 PCF, and 40 PCF).

 (Asteraceae, Heliantheae), a winged cypselae new species of for Brazil.

We describe one new species from Ceará state, Brazil: . It is morphologically associated with , but distinguished by 0.25-1.

Advancing continuous flow techniques in effective trimethoprim oxidation: combatting bacterial resistance in wastewater.

This work describes an innovative catalytic process for aqueous trimethoprim degradation, using a fixed-bed continuous flow reactor packed with a manganese(III) -substituted porphyrin covalently immobilized functionalized aminopropyl silica gel as the catalyst and HO as a green oxidant. It exhibits remarkable activity and stability, maintaining its performance over extended periods (up to 8 hours) and achieving significant reductions in total organic carbon (TOC = 80%). Importantly, microbiological assays confirmed that this degradation process effectively converts trimethoprim into non-resistance-inducing products.

Effects of Probiotic Therapy on Periodontal and Peri-implant Treatments: An Umbrella Review.

Introduction: The effectiveness of nonsurgical periodontal treatment is related to patient- and tooth-related factors. To overcome the limitations of the conventional approach, probiotics are one of the adjunct therapies that have been studied.

Objectives: This umbrella review answered the focused question: in adult patients with periodontal diseases or peri-implant diseases, does the use of probiotic therapy as an adjuvant to nonsurgical periodontal treatment when compared with nonsurgical periodontal treatment alone affect treatment effectiveness and clinical disease parameters?

Methods: A systematic electronic search to identify systematic reviews according to PICOS criteria, defined a priori, was used, and 5 electronic databases were searched (Medline, LILACS, Cochrane Central Registry of Controlled Trials, Google Scholar, and DANS EASY).

Enhancing the light yield of He:CF based gaseous detector.

The CYGNO experiment aims to build a large ( m ) directional detector for rare event searches, such as nuclear recoils (NRs) induced by dark matter (DM), such as weakly interactive massive particles (WIMPs). The detector concept comprises a time projection chamber (TPC), filled with a He:CF 60/40 scintillating gas mixture at room temperature and atmospheric pressure, equipped with an amplification stage made of a stack of three gas electron multipliers (GEMs) which are coupled to an optical readout. The latter consists in scientific CMOS (sCMOS) cameras and photomultipliers tubes (PMTs).

A health system assessment approach to analysis of political parties' health proposals, Portugal.

Problem: Comparing health policy measures before elections and identifying potential gaps in the health policy debate can be challenging.

Approach: We explored the use of the Health System Performance Assessment for Universal Health Coverage framework to analyse health policy proposals by classifying health policy measures outlined in political manifestos into four health system functions: governance, financing, resource generation and service delivery. As a case study, we analysed the political manifestos of all Portuguese parties with parliamentary representation ahead of the election in March 2024.

Differential effects of chronic and intermittent administration of taurine on alcohol binge drinking in male rats.

Episodic consumption of high doses of alcohol in a short period (binge drinking - BD) among adolescents is known to be harmful to their brain development. Chronic use of taurine increases voluntary alcohol consumption and shows an anxiolytic-like effect in rats. In this study, we evaluated the differential effects of chronic and intermittent taurine administration on alcohol consumption and behavioral changes in adolescent and young adult rats subjected to the BD model.

Impact of Multi-Professional Intervention on Health-Related Physical Fitness and Biomarkers in Overweight COVID-19 Survivors for 8 and 16 Weeks: A Non-Randomized Clinical Trial.

Background/objectives: Considering the diverse symptomatology of COVID-19-ranging from mild to severe cases-multi-professional interventions are crucial for enhancing physical recovery, nutritional status, and mental health outcomes in affected patients. Thus, this study aimed to investigate the effects of such an intervention on health-related physical fitness and biomarkers in overweight COVID-19 survivors with varying degrees of symptom severity after 8 weeks and 16 weeks.

Methods: This non-randomized clinical trial included 59 overweight COVID-19 survivors (32 males and 27 females) divided into three groups: mild ( 31), moderate ( 13), and severe/critical ( 15).

Addressing disruptive medical staff behavior: a 3-year experience.

Background: Menezes et al. describe their experience with the diagnosis and management of disruptive medical staff behavior in a private hospital between 2020 and 2022. Surgical medical specialties were found to demonstrate the highest prevalence of such behavior, and continual education of physicians regarding appropriate workplace behavior was found to be the most important management strategy to prevent unsafe work environments and strengthen an appropriate culture of safety.

Probiotics in the non-surgical treatment of periodontitis: a systematic review and network meta-analysis.

This systematic review and network meta-analysis aimed to assess the impact of combining professional mechanical plaque removal (PMPR) with probiotics compared to PMPR + placebo on probing pocket depth (PPD) and clinical attachment level (CAL). Randomized controlled trials published until November 2023 were searched across electronic databases, peer-reviewed journals, and grey literature. Two authors independently selected, extracted data, and assessed bias risk.

Health-Related Physical Fitness and Biochemical Parameters in Overweight Older People during Social Isolation Imposed by the COVID-19 Pandemic: A Longitudinal and Observational Study.

With COVID-19, evidence indicates that the elderly will have worse biochemical markers related to health in social isolation. The objective was to analyze the impacts on physical fitness and biochemical parameters of older adults' health during COVID-19 social isolation. Quantitative, longitudinal, and observational study was conducted between 2020, 2021, and 2022.

Medication-Related Osteonecrosis of the Jaw: A Systematic Review of Case Reports and Case Series.

Medication-related osteonecrosis of the jaw (MRONJ) is a rare condition, typically seen in patients receiving antiresorptive or antiangiogenic drugs. This study aims to synthesize reports and case series of MRONJ regarding sociodemographic and clinical characteristics and to evaluate the effectiveness of the treatments applied. Following PRISMA guidelines, a search for case reports and case series was carried out in the PubMed-Medline database until March 2024.

Calcium Silicate-Based Cements in Restorative Dentistry: Vital Pulp Therapy Clinical, Radiographic, and Histological Outcomes on Deciduous and Permanent Dentition-A Systematic Review and Meta-Analysis.

Vital pulp therapy aims to preserve the vitality of dental pulp exposed due to caries, trauma, or restorative procedures. The aim of the present review was to evaluate the clinical, radiographic, and histological outcomes of different calcium silicate-based cements used in vital pulp therapy for both primary and permanent teeth. The review included 40 randomized controlled trials from a search across PubMed, LILACS, and the Cochrane Collaboration, as well as manual searches and author inquiries according to specific inclusion and exclusion criteria.

Predisposing and precipitating factors for the development of postoperative delirium in critically ill patients in a university intensive care unit.

Objective: to detect the incidence of postoperative delirium in critically ill patients admitted to a surgical intensive care unit and to evaluate the predisposing and precipitating factors associated with postoperative delirium in critically ill patients admitted to a surgical intensive care unit.

Method: this is a prospective cohort study of 157 critically ill surgical patients. Fisher's exact test and Chi-square test were used for the association between factors and the occurrence of delirium, the Wilcoxon test for numerical variables, and the logistic regression model for the analysis of predisposing and precipitating factors.

DNA methylation and histone modifications associated with antipsychotic treatment: a systematic review.

Antipsychotic medications are essential when treating schizophrenia spectrum and other psychotic disorders, but the efficacy and tolerability of these medications vary from person to person. This interindividual variation is likely mediated, at least in part, by epigenomic processes that have yet to be fully elucidated. Herein, we systematically identified and evaluated 65 studies that examine the influence of antipsychotic drugs on epigenomic changes, including global methylation (9 studies), genome-wide methylation (22 studies), candidate gene methylation (16 studies), and histone modification (18 studies).

Supplementation of l-arginine in pregnant gilts affects the protein abundance of DNMT1 in 35-day fetuses.

Maternal nutrition is one of the main environmental factors regulating gene expression during fetal development through epigenetic modifications. Some nutrients, such as the amino acid l-arginine, are added to maternal diets to modulate gene expression, improve the reproductive performance of females, and enhance conceptus development. This study investigated the hypothesis that supplementation of pregnant gilts with l-arginine regulates gene expression in conceptuses through epigenetic mechanisms.