Lingual thyroid: a rare cause of difficult intubation.

This case report is about a patient with an oropharyngeal mass presenting to our hospital for biopsy under general anesthesia. Because of the great risk of failure of mask ventilation and direct laryngoscopy, an awake fiberoptic intubation was performed successfully. The biopsy revealed a thyroid tissue leading to the diagnosis of ectopic lingual thyroid.

Early-onset breast cancer in a Lebanese family with Lynch syndrome due to MSH2 gene mutation.

Background: There are still controversies about the integration of breast cancer as a part of the disease spectrum in Lynch syndrome.

Methods: A regular follow-up of a Lebanese pedigree with Lynch syndrome due to a point mutation of MSH2 gene at the splice donor site of intron 3 started in 1996.

Results: A 26-year-old pregnant woman, mutation carrier, developed an aggressive breast cancer, refractory to standard chemotherapy regimens.