Stability Indices to Deciphering the Genotype-by-Environment Interaction (GEI) Effect: An Applicable Review for Use in Plant Breeding Programs.

Experiments measuring the interaction between genotypes and environments measure the spatial (e.g., locations) and temporal (e.

Optimization of parameters affecting on CHO cell culture producing recombinant erythropoietin.

Several factors may affect erythropoietin (EPO) sugar structures including designing cell culture procedure, pH, concentration of additives, dissolved oxygen, and other physicochemical parameters. In this study, we investigated the influence of changes in effective parameters and compounds on the growth rate of Chinese hamster ovary cell (CHO) cells producing recombinant EPO. Cell culture was performed at different temperature, buffering conditions, and varied concentrations of additives such as pyruvic acid, insulin, GlutaMAX, and sodium butyrate.