Purpose: The purpose of this study was to evaluate the effect of implant abutment material on peri-implant soft tissue color using intraoral spectrophotometric analysis and to compare the clinical outcomes with patient and clinician perception and satisfaction.
Materials And Methods: Thirty patients and four prosthodontic faculty members participated. Abutments were zirconia, gold-hued titanium, and titanium.
Objective: Little is known about genetic contributors to higher than usual warfarin dose requirements, particularly for African Americans. This study tested the hypothesis that the γ-glutamyl carboxylase (GGCX) genotype contributes to warfarin dose requirements greater than 7.5 mg/day in an African American population.
View Article and Find Full Text PDFStudy Objective: To test the hypothesis that genotypes for proteins affecting vitamin K availability influence the duration of time required to achieve a stable warfarin dose in African-American patients.
Design: Retrospective cohort study.
Setting: Pharmacist-managed antithrombosis clinic.
Statement Of Problem: Clinicians must know if a new screw can predictably increase reverse torque after multiple screw insertion cycles.
Purpose: The purpose of this study was (1) to compare the effect of multiple implant prosthetic screw insertion and removal cycles on reverse torque, (2) to determine whether a new screw, after multiple screw insertion cycles, affects reverse torque, and (3) to assess implant and prosthetic screw thread surface morphology with scanning electron microscopy (SEM).
Material And Methods: One primary screw was paired with an implant (MT Osseospeed) and inserted to 25 Ncm torque 9, 19, 29, or 39 times (n=10).
Blood Cells Mol Dis
February 2011
While Hispanics are the largest and most rapidly growing minority population in the United States, they are underrepresented in pharmacogenomic studies with warfarin. We sought to determine the combination of clinical and genetic influences of warfarin dose requirements in Hispanics. In addition, we tested the performance of published warfarin dosing algorithms derived from largely non-Hispanic cohorts in an inner-city U.
View Article and Find Full Text PDFStudy Objective: To identify patient-specific factors associated with spironolactone-induced potassium level elevation in patients with heart failure.
Design: Prospective cohort study.
Setting: Two adult heart failure clinics.
Purpose: To evaluate the Minolta CR-400 chromameter in objectively measuring periocular/facial pigmentation in subjects of different ethnicities.
Methods: The CR-400 was used to obtain skin color measurements from 75 African-American, Caucasian and Hispanic subjects in 16 facial and periocular locations. Comparisons between ethnic and Fitzpatrick groups and instrument reliability were analyzed.
Study Objective: To determine whether beta-blocker dose influences cardiac collagen turnover and the effects of spironolactone on cardiac collagen turnover in patients with heart failure.
Design: Prospective clinical study.
Setting: Two heart failure centers.
Background And Purpose: The durability of aneurysm coil embolization is thought to depend on packing density. The expansile property of hydrogel coating on coils increases volumetric packing per coil length. We describe our experience using hydrogel-coated coils (HydroCoils) compared with inert platinum coils in intracranial aneurysm embolization.
View Article and Find Full Text PDFBackground: There is substantial interpatient variability in response to aspirin after an ischemic stroke or transient ischemic attack (TIA), as assessed by ex vivo effects of aspirin on platelet aggregation. The factors contributing to this variability are not well defined.
Objective: To determine whether demographic, social, or clinical characteristics are associated with ex vivo response to aspirin in patients with a history of stroke or TIA.
Study Objective: To determine whether the effects of spironolactone on potassium homeostasis vary by race by comparing serum potassium concentrations and potassium supplement use in African-American and Caucasian patients receiving spironolactone for heart failure.
Design: Retrospective medical record review.
Setting: Two heart failure centers.