Are Patients with Perforated Peptic Ulcers Who are Negative for at a Greater Risk?

The link between infection and peptic ulceration is well established. Recent studies have reported a decrease of -related peptic ulcer disease; eradication is likely the cause of this decrease. We hypothesized that patients with -positive perforated peptic ulcer disease (PPUD) requiring surgical intervention had worse outcomes than patients with -negative PPUD.