MED13 Gene Mutation Related to Autism Spectrum Disorder: A Case Report.

This case report highlights an association between the MED13 gene and autism spectrum disorder (ASD). ASD is a neurodevelopmental disorder characterized by impaired social interactions, communication difficulties, and repetitive behaviors. The MED13 gene encodes a subunit of the Mediator complex, which plays a key role in gene expression regulation and transcriptional processes.

Transcreation matters: A learner centric participatory approach for adapting cancer prevention messages for Latinos.

Background: Advancing health equity requires innovative patient education approaches for adapting English-language evidence-based interventions (EBIs) to resonate with multicultural, multilingual audiences.

Objective: Examine the benefit, functionality, and practical considerations of transcreation (translation + cultural adaptation) as a critical and salient learner-centric process for developing a Spanish-language intervention (photonovella + video): Un examen sencillo para un colon saludable (A simple test for a healthy colon).

Patient/community Involvement: We involved patients/community members in a participatory reflective process, from problem identification to intervention design, development, delivery, and impact measurement.

Lay navigator model for impacting cancer health disparities.

This paper recounts experiences, challenges, and lessons learned when implementing a lay patient navigator program to improve cancer care among medically underserved patients who presented in a primary care clinic with a breast or colorectal cancer abnormality. The program employed five lay navigators to navigate 588 patients. Central programmatic elements were the following: (1) use of bilingual lay navigators with familiarity of communities they served; (2) provision of training, education, and supportive activities; (3) multidisciplinary clinical oversight that factored in caseload intensity; and (4) well-developed partnerships with community clinics and social service entities.

A cluster randomized trial evaluating the efficacy of patient navigation in improving quality of diagnostic care for patients with breast or colorectal cancer abnormalities.

Background: This study examines efficacy of a lay patient navigation (PN) program aimed to reduce time between a cancer abnormality and definitive diagnosis among racially/ethnically diverse and medically underserved populations of Tampa Bay, Florida.

Methods: Using a cluster randomized design, the study consisted of 11 clinics (six navigated; five control). Patients were navigated from time of a breast or colorectal abnormality to diagnostic resolution, and to completion of cancer treatment.

Creating a patient navigation model to address cervical cancer disparities in a rural Hispanic farmworker community.

This report describes the implementation of a pilot patient navigation (PN) program created to address cervical cancer disparities in a predominantly Hispanic agricultural community. Since November 2009, a patient navigator has provided services to patients of Catholic Mobile Medical Services (CMMS). The PN program has resulted in the need for additional clinic sessions to accommodate the demand for preventive care at CMMS.

Addressing cancer disparities through community engagement: improving breast health among Haitian women.

Purpose/objectives: To describe processes for fostering community engagement among Haitian women to facilitate breast health education and outreach that are consonant with Haitians' cultural values, literacy, and linguistic skills.

Data Sources: Existing breast cancer education and outreach efforts for Haitian immigrant communities were reviewed. Local community partners were the primary source of information and guided efforts to create a series of health-promoting activities.

Focus groups in the design of prostate cancer screening information for Hispanic farmworkers and African American men.

Purpose/objectives: To gain a better understanding of men's everyday concerns as part of formative research for creating relevant prostate cancer screening education; to describe methods and processes used to conduct community-based focus groups.

Setting: Community-based settings in catchment areas surrounding Tampa, FL.

Sample: 8 community-based focus groups: a total of 71 Hispanic farmworkers and African American men.

Screening and community outreach programs for priority populations: considerations for oncology managers.

The goals of screening and community outreach efforts are to translate knowledge into relevant interventions to enhance health, prevent disease and manage chronic illness. Despite recent progress in the fight against cancer, a disproportionate share of the cancer burden is observed among ethnic minorities and medically underserved populations. Studies consistently link low socioeconomic status to low survival rates for nearly all types of cancer.