The "replication crisis" in the public eye: Germans' awareness and perceptions of the (ir)reproducibility of scientific research.

Several meta-analytical attempts to reproduce results of empirical research have failed in recent years, prompting scholars and news media to diagnose a "replication crisis" and voice concerns about science losing public credibility. Others, in contrast, hoped replication efforts could improve public confidence in science. Yet nationally representative evidence backing these concerns or hopes is scarce.

Evaluation of an interdisciplinary therapy algorithm in patients with prosthetic joint infections.

Purpose: Current concepts in the treatment of prosthetic joint infections include prosthetic retention and exchange strategies according to published recommendations. A useful algorithm should fit for each type of prosthetic joint infection, even the most complicated situations. We present the outcome of 147 patients with prosthetic joint infections of the hip or the knee joint in an unselected population in clinical routine.

Computer-assisted fluoroscopic navigation of percutaneous spinal interventions.

Purpose: Percutaneous spine procedures may occasionally be difficult and subject to complications. Navigation using a dynamic reference base (DRB) may ease the procedure. Yet, besides other shortcomings, its fixation demands additional incisions and thereby defies the percutaneous character of the procedure.

Intravertebral pressure gradient during vertebroplasty.

Objective: Intravertebral pressure (IP) is considered a possible factor influencing cement leakage in vertebroplasty (VP). Reports of measuring IP during the injection of the cement reveal rather low values in the periphery of the vertebral body but fail to determine the situation in the center. Hypothesizing there is a significant IP gradient between both areas intravertebral pressure measurements were conducted in a comparative biomechanical study.

Early polyethylene wear and excessive acetabular granuloma in an uncemented HA-coated total hip arthroplasty--midterm results of a prospective study.

This is a prospective review of 135 HA-coated ABG I total hip arthroplasty (THA) systems with a mean clinical and radiographic follow-up of 8.5 years. The 5-year survival rate was 85%, but 22% of the patients were dissatisfied.

Intravertebral pressure during vertebroplasty and balloon kyphoplasty: an in vitro study.

Study Design: Intravertebral pressure (IP) measurements were conducted on human cadaveric lumbar spines in a biomechanical study.

Objective: To assess the pressure that is generated in the center of the vertebral body during the cement fill in vertebroplasty (VP) and balloon kyphoplasty (BKP).

Summary Of Background Data: High IP during polymethylmethacrylate (PMMA) injection have frequently been raised as a reason for the higher cement leakage rate during VP in contrast to BKP.

Epithelioid sarcoma in the thoracic spine.

Epithelioid sarcoma is a rare and highly malignant soft tissue tumor that is commonly found in the extremities and rarely in the trunk area. This malignant tumor often mimics granuloma or nodular fasciitis, which causes a delay in establishing the diagnosis. This type of cancer has a high recurrence rate.

Therapeutic options and results following fixed atlantoaxial rotatory dislocations.

Atlantoaxial rotatory dislocation (AARD) represents a rare pathological condition of the upper cervical spine that is frequently misdiagnosed, leading to a delay in therapy. In a long-term assessment of clinical and radiological results, three different therapeutic options with regard to the length of the dislocation-therapy interval (DTI) were evaluated. Twenty-six patients were treated for AARD from December 1988 until April 2000.