Publications by authors named "Markku E Komu"
Background: Diffusion tensor parameters can be analysed by fitting regions of interest (ROIs) to selected brain structures. The clinical usefulness of these measurements is influenced by their reproducibility and validity.
Objective: To investigate the reproducibility of fractional anisotropy (FA) and mean diffusivity (MD) measurements.
Article Synopsis
- The study aimed to assess two methods—liver-to-muscle signal intensity and R2*—for measuring liver iron levels with potential clinical applications.
- Research involved 16 liver phantoms and 33 human subjects using three different MRI scanners, which showed strong correlations between the MRI results and actual iron concentrations in both phantoms and human subjects.
- Both methods proved reliable for indicating iron levels, with R2* showing consistency across different scanners, although further testing is necessary to confirm their transferability to various devices.
The purpose of this study was to show the T(1rho) dispersion profile in various rat tissues (liver, brain, spleen, kidney, heart and skeletal muscle) at low (0.1 T) B(0) field at very low locking field B1, starting from 10 microT. The T(1rho) dispersion profile showed a quite similar pattern in all tissues.
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