Publications by authors named "Markhabat Kairova"
Peptidoglycan Hydrolases of Local Lactic Acid Bacteria from Kazakh Traditional Food.
Cent Asian J Glob Health
January 2014
Introduction: Peptidoglycan (PG) is a major component of the cell wall of Gram-positive bacteria and is essential for maintaining the integrity of the bacterial cell and its shape. The bacteria synthesize PG hydrolases, which are capable of cleaving the covalent bonds of PG. They also play an important role in modeling PG, which is required for bacterial growth and division.
View Article and Find Full Text PDFDetecting interferon-gamma release from human CD4 T-cells using surface plasmon resonance.
Colloids Surf B Biointerfaces
October 2010
Article Synopsis
- The study focuses on measuring cytokine secretion from leukocytes, particularly CD4 T-cells, which is crucial for understanding immune responses to diseases.
- The researchers combined antibody-based cell separation with surface plasmon resonance (SPR) technology to capture CD4 T-cells and detect the inflammatory cytokine interferon-gamma (IFN-gamma) without labeling.
- The results showed a correlation between the SPR signal and the actual cytokine production, suggesting this method could be useful for detecting various secreted proteins from specific cell types in the future.