Publications by authors named "Mark deBelder"
Article Synopsis
- Coronary perforation during acute coronary syndrome percutaneous coronary interventions (ACS-PCI) is rare, occurring in 0.37% of procedures, with consistent annual rates between 2007 and 2014.
- Key predictors of coronary perforation include older age, female gender, chronic total occlusion interventions, and the use of multiple stents or rotational atherectomy, while different P2Y12 inhibitors did not show a significant effect.
- The occurrence of coronary perforation is linked to worse clinical outcomes, and the use of glycoprotein inhibitors (GPI) is associated with increased rates of tamponade, highlighting the need for careful consideration of these factors in ACS-PCI procedures.
Aims: To study the association between time of hospitalization and in-hospital mortality for acute myocardial infarction (AMI).
Methods And Results: Patients admitted with ST-elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI) across 243 hospitals in England and Wales between 1 January 2004 and 31 March 2013 were included. The outcome measure was in-hospital mortality.
Objectives: Previous studies indicate frailty to be associated with poor outcomes following transcatheter aortic valve implantation (TAVI), but there is limited evidence from multicentre registries. The aim was to investigate the independent association of frailty with TAVI outcomes, and the prognostic utility of adding frailty into existing clinical prediction models (CPMs).
Design: The UK TAVI registry incorporated three frailty measures since 2013: Canadian Study of Health and Ageing, KATZ and poor mobility.
Article Synopsis
- CP during CTO-PCI is a rare but serious complication, occurring in 1.40% of procedures analyzed from a large national database.
- Patient factors like age and female sex, as well as complex procedural strategies, increase the risk of CP.
- Adverse outcomes such as myocardial infarction and increased 12-month mortality are significantly more common in patients experiencing CP.
Incidence, Determinants, and Outcomes of Coronary Perforation During Percutaneous Coronary Intervention in the United Kingdom Between 2006 and 2013: An Analysis of 527 121 Cases From the British Cardiovascular Intervention Society Database.
Circ Cardiovasc Interv
August 2016
Background: As coronary perforation (CP) is a rare but serious complication of percutaneous coronary intervention (PCI) the current evidence base is limited to small series. Using a national PCI database, the incidence, predictors, and outcomes of CP as a complication of PCI were defined.
Methods And Results: Data were prospectively collected and retrospectively analyzed from the British Cardiovascular Intervention Society data set on all PCI procedures performed in England and Wales between 2006 and 2013.
Background: Patients with "refractory angina" (RA) unsuitable for coronary revascularization experience high levels of hospitalization and poor health-related quality of life. Randomized trials have shown spinal cord stimulation (SCS) to be a promising treatment for chronic stable angina and RA; however, none has compared SCS with usual care (UC). The aim of this pilot study was to address the key uncertainties of conducting a definitive multicenter trial to assess the clinical and cost-effectiveness of SCS in RA patients, i.
View Article and Find Full Text PDFBackground: The management and impact of concomitant coronary artery disease in patients referred for TAVI remains contentious. We describe the prevalence, clinical impact and management of coronary artery disease (CAD) in patients in the United Kingdom TAVI Registry.
Methods: All-inclusive study of patients undergoing TAVI in the United Kingdom (excluding Northern Ireland) from January 2007 to December 2011.
Objective: The aim of the current study was to identify predictors of paraprosthetic aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) and examine its influence on short/medium-term mortality using the UK TAVI Registry. TAVI is an effective treatment for high-risk patients with severe symptomatic aortic stenosis (AS), but paraprosthetic AR has been associated with increased in-hospital and mid-term mortality.
Methods: Between January 2007 and December 2011, 2584 TAVI procedures were performed in the UK.