Publications by authors named "Mark Zaontz"

Article Synopsis
  • Testicular torsion is an emergency condition requiring timely surgery to either save or remove the affected testis, with urgency emphasizing the need to minimize ischemia time.* -
  • The study aimed to explore how patient transfer impacts surgical outcomes, particularly focusing on race and socioeconomic factors, while determining the critical cutoff times for surgery to preserve the testis.* -
  • Findings indicated that race and socioeconomic status did not significantly influence surgical success, but factors like age and timing from symptom onset were crucial, with optimal cutoffs identified at 10.5 hours for presentation and 14.5 hours for detorsion.*
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Article Synopsis
  • Hypospadias repair often leads to complications, and while factors like anatomy and surgeon experience are known contributors, the influence of social determinants of health on outcomes is less understood.
  • The study aimed to explore how resources and community conditions, assessed through the Childhood Opportunity Index (COI), impact post-operative complications in children who underwent distal hypospadias repair.
  • An analysis of 938 patients showed a 14.1% complication rate, but no significant correlations were found between COI, insurance type, race, and complications; however, anatomical factors like glans width and chordee degree were linked to complications.
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Article Synopsis
  • - The study investigates non-operative management of pediatric ureteroceles, finding that this approach leads to less frequent and later secondary surgical interventions compared to those who undergo immediate surgery.
  • - Successful non-operative treatment is linked to factors such as smaller ureterocele size, absence of high-grade vesicoureteral reflux (VUR), and fewer comorbidities among patients.
  • - Despite these findings, there is still no standard method for choosing which patients should receive non-operative care, highlighting the need for more consensus in managing ureteroceles.
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Circumcision is commonly performed but anatomic variants occur and can affect outcomes if not addressed properly. The combination of concealed penis and penoscrotal webbing is fairly common and presents across a spectrum of severity. If not repaired, this can result in a buried penis that can cause penile adhesions, wound healing concerns, and make the penis appear shorter secondary to a retracted position.

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Purpose: Testosterone administration prior to hypospadias repair is common practice among pediatric urologists; however, its impact on surgical outcomes remains controversial. We hypothesize that testosterone administration prior to distal hypospadias repair with urethroplasty significantly decreases postoperative complications.

Materials And Methods: We queried our hypospadias database for primary distal hypospadias repairs with urethroplasty from 2015 to 2021.

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Introduction: The use of caudal anesthesia at the time of hypospadias repair remains controversial as some prior studies have reported increased postoperative complication rates associated with caudal nerve block. However, these results have been called into question due to confounding factors and heterogeneous study groups.

Objective: Given the importance of identifying true risk factors associated with increased hypospadias complication rate, we examined our experience with caudal anesthesia limiting our analysis to distal repairs.

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CHD7 disorder is a multiple congenital anomaly syndrome with a highly variable phenotypic spectrum, and includes CHARGE syndrome. Internal and external genital phenotypes frequently seen in CHD7 disorder include cryptorchidism and micropenis in males, and vaginal hypoplasia in females, both thought to be secondary to hypogonadotropic hypogonadism. Here, we report 14 deeply phenotyped individuals with known CHD7 variants (9 pathogenic/likely pathogenic and 5 VOUS) and a range of reproductive and endocrine phenotypes.

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Introduction & Objective: The opioid crisis has raised concerns for long-term sequela of routine administration of opioids to patients, particularly in the pediatric population. Nonsteroidal anti-inflammatory drug use is limited in hypospadias surgery due to concerns for post-operative bleeding, particularly with ketorolac. We hypothesize that ketorolac administration at the time of hypospadias repair is not associated with increased bleeding or immediate adverse events.

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Introduction And Objective: Opioid stewardship is recognized as a critical clinical priority. We previously reported marked reductions in narcotic administration after implementation of an opioid reduction protocol for pediatric ambulatory urologic surgery. We hypothesize that a decrease in post-operative and discharge opioid administration will not increase short-term adverse events.

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Objective: To report on our experience performing office-based pediatric urologic procedures. We hypothesize that office-based interventions are safe and effective for children, avoiding unnecessary risk and cost associated with general anesthesia.

Methods: We retrospectively identified patients undergoing office-based interventions from 2014 to 2019, including lysis of penile or labial adhesions, division of skin bridges, meatotomy and excision of benign lesion.

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Purpose: Testosterone (T) administration prior to hypospadias surgery to increase glans size remains controversial. Understanding T's effect on glans width (GW) is essential to understanding its potential impact on surgical outcomes. We hypothesized that preoperative T in prepubertal boys significantly increases GW at the time of hypospadias surgery.

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Introduction: Meatal and fossa navicularis stricture after hypospadias repair is a challenging condition. A range of management techniques have been applied to treat meatal and fossa navicularis stenosis but, as yet, there is no consensus as to the best method. Open urethroplasty with oral mucosal graft (OMG) has been widely accepted to be the gold standard in repairing the stricture.

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Introduction: Widespread utilization of telemedicine in our practice to date has been limited to the evaluation of certain post-surgical patients. The COVID-19 pandemic acutely stressed our established system and required us to enhance our utilization of telemedicine. We hypothesized that expansion of telemedicine to new and follow up patient visits for pediatric urology could be done effectively in a way that satisfied patient and parental expectations.

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Article Synopsis
  • - The study investigates the risk factors for infertility in adolescent boys with varicocele, focusing on the relationship between hormone levels, testicular volume, and semen quality, specifically total motile sperm count.
  • - Researchers reviewed data from 78 Tanner stage 5 boys to analyze correlations between sperm count and various hormone levels, finding that follicle-stimulating hormone inversely correlated with sperm count, while inhibin B and total testicular volume showed a direct positive correlation.
  • - The results suggest that specific hormone and testicular volume thresholds can help predict abnormal sperm counts, indicating potential clinical measures to assess fertility risk in boys with varicocele.
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Purpose: Controversy remains within the pediatric urology community regarding adequate duration of followup after hypospadias repair. Some have suggested that minimal long-term followup is necessary due to a low incidence of late complications. The objective of this study was to delineate time to complication detection for primary hypospadias repairs.

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