Clinical utility of the endometrial receptivity analysis in women with prior failed transfers.

Purpose: To determine the utility of the endometrial receptivity analysis (ERA) in women with prior failed embryo transfers (ET).

Methods: This was a retrospective study of patients who underwent an ERA test with a subsequent frozen ET. Women were classified based on their indication for an ERA test: (1) ≥ 1 prior failed ET (cases), or (2) as a prophylactic measure (controls).

Chromosome abnormalities in embryos derived from microsurgical epididymal sperm aspiration and testicular sperm extraction.

Objective: To evaluate the patterns of chromosome abnormalities in embryos derived from intracytoplasmic sperm injection (ICSI) in microsurgical epididymal sperm aspiration (MESA) or testicular sperm extraction (TESE) in comparison to embryos that are derived from naturally ejaculated (EJAC) patients.

Materials And Methods: Male partners with azoospermia who required MESA or TESE for ICSI were studied for chromosomal abnormalities. The ICSI patients with EJAC sperm served as the control group.

Saving time during laparoscopy using a new, wall anchoring trocar device.

Objective: Safe and reliable access systems are crucial in laparoscopy, and trocar dislodgement is still a common and frustrating problem. Wall emphysema can occur besides the risky prolongation of the surgical procedure. Wall-anchoring components provide a better hold of the device.

Successful outcome after preimplantation genetic screening and very delayed embryo transfer.

We report the positive outcome of a delayed single ET of a preimplantation genetic screening-defined embryo in an otherwise routine case of IVF-ET. To our knowledge, this is the first report of a fresh ET 48 hours longer than what is generally considered the limit of days after egg retrieval (six) to safely perform an ET.

Is gender selection an appropriate use of medical resources?

Gender selection by PGD is an appropriate use of medical resources. Children borne through PGD for gender determination would be welcome and would come into a couple's life at a planned, opportune time. If the practice were made more available through insurance coverage, the size and makeup of families could become a matter of choice rather than chance for couples favoring this approach.

Effect of prolonged gonadotropin-releasing hormone agonist therapy on the outcome of in vitro fertilization-embryo transfer in patients with endometriosis.

Objective: To evaluate the effect of a 3-month course of GnRH agonist administered immediately before IVF-ET in infertile patients with endometriosis.

Design: Prospective, randomized trial.

Setting: Three tertiary care assisted reproductive technology programs.