Publications by authors named "Mark Schwade"
Paws and Pathogens: A Multidisciplinary Approach Through Endocarditis and Hepatosplenic T-Cell Lymphoma.
J Investig Med High Impact Case Rep
July 2024
Article Synopsis
- Gram-negative coccobacilli are important pathogens that can lead to zoonotic infections in humans, especially causing infective endocarditis, which can be hard to diagnose.
- A 23-year-old male initially misdiagnosed with lymphoma was actually suffering from blood culture-negative endocarditis linked to these bacteria, showing symptoms like fevers, pancytopenia, and heart issues despite negative blood tests.
- The case emphasizes the need for careful consideration of these pathogens in patients with suspected endocarditis and highlights the importance of serological testing and a comprehensive treatment strategy for better patient outcomes.
Value of D-Dimer in Risk Stratification for Thromboembolism in Patients With Atrial Fibrillation and Low CHA2DS2-VASc Score.
J Investig Med High Impact Case Rep
April 2023
Atrial fibrillation (AF) can cause thrombi formation and subsequent emboli deposition in systemic arteries, leading to various organ ischemia and infarction. Anticoagulation therapy can reduce the risk of thrombus formation and embolization, and is initiated based on a patient's risk score, which is frequently estimated with the CHA2DS2-VASc score. We present a case of thromboembolism (TE) where a low CHA2DS2-VASc score suggested a low-moderate risk of systemic embolization, but an elevated plasma D-dimer value prompted further investigation which revealed an intracardiac thrombus with renal embolism.
View Article and Find Full Text PDFBackground: Psoriasis impairs the quality of life of approximately 7.5 million Americans and is associated with serious comorbidities. Because of chronic vascular access and epidermal dysfunction, end-stage renal disease (ESRD) patients with psoriasis may be at greater risk for infection, and psoriasis treatment could affect this risk.
View Article and Find Full Text PDFArticle Synopsis
- Spinal epidural abscess (SEA) is a serious infection affecting the epidural space, with end-stage renal disease (ESRD) patients being especially vulnerable, yet little research has analyzed this specific demographic within the United States Renal Data System (USRDS).
- A study used USRDS data to identify 1,697 ESRD patients diagnosed with SEA from 2005 to 2010, revealing that males, black individuals, and those with diabetes or catheter access were more prone to SEA, and various infections increased the risk significantly.
- The study also found that older age, urinary tract infections, decubitus ulcers, and paraplegia after SEA were linked to higher mortality rates
Background: The association of shiftwork and the risk of obesity in nurses has been inconsistent in the literature.
Objectives: We therefore conducted a systematic review and meta-analysis to quantitatively summarize this association in nurses.
Methods: We systematically searched PubMed, Ovid MEDLINE, Cochrane Library, EMBASE and Web of Science from inception until April 2020 for studies that examined the relationship between shift work and obesity in nurses.
Article Synopsis
- Resuming social participation is a key goal of post-stroke rehabilitation, and exercise-based interventions are effective but their comparative effectiveness is not fully clear.
- A network meta-analysis was conducted on 16 randomized control trials with 1704 stroke patients to evaluate the effectiveness of various exercise interventions on social participation.
- The findings showed that a motor relearning program is the most effective short-term exercise intervention, while home-based combined exercise is the best for long-term improvements in social participation.
Background: Arthritis is one of the most common comorbidities in heart failure (HF) patients, and is associated with decreased activity levels. Few studies have examined sedentary behavior (SB) in HF patients with arthritis, and little is known about the factors that may influence SB in this population.
Methods: This is a retrospective, secondary analysis using data collected from a randomized control trial.
Background: Cardioversion in patients with atrial fibrillation (AF) can cause cardioembolic stroke, and effective clinical management is necessary to reduce morbidity and mortality. Currently, transesophageal echocardiography (TEE) is the accepted standard to diagnose cardiogenic thromboemboli; however, a negative TEE does not eliminate the possibility of left atrial thrombus. The objective of this study was to evaluate the diagnostic value of supplementing the TEE with additional noninvasive markers to ensure thrombus absence.
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