Publications by authors named "Mark S Garcia"
Nat Struct Mol Biol
April 2011
Article Synopsis
- Telomeres protect chromosome ends from degradation and disruptions, but the specific mechanisms behind this protection are not completely understood.
- In budding yeast, the Cdc13 protein is crucial for telomere capping, and defective capping occurs in certain mutants, especially at high temperatures.
- The study shows that stabilizing G-quadruplex (G4) DNA through various treatments can compensate for cdc13-1 capping issues, highlighting G4 DNA's potential protective role at telomeres even when normal capping is absent.
