Peripapillary hyperreflective ovoid mass-like structures and the retinal nerve fiber layer thinning.

Aim: We describe a report of three cases of bilateral Peripapillary Hyperreflective Ovoid Mass-Like Structures (PHOMS), their respective multimodal imaging, and retinal nerve fiber layer (RNFL) analysis over time.

Methods: We performed an elaborated multimodal imaging of three pediatric patients with PHOMS. We performed a visual acuity testing, followed by a biomicroscopic and fundus examination, an additional Optical Coherence Tomography (OCT), fundus autofluorescence (FAF), infra-red (IR), fluorescein angiography (FA), Scanning laser Ophtalmoscopy (SLO), and retro-mode imaging.

Fundus autofluorescence of retinal atrophy progression between fundus flavimaculatus and extensive macular atrophy with pseudo-drusen.

Objective: To analyze the progression of macular atrophy in Fundus Flavimaculatus (FFM) versus Extensive Macular Atrophy with Pseudo-drusen (EMAP), using Spectralis® RegionFinder™ tool.

Methods: Retrospective review of patients diagnosed with FFM and EMAP. Ophthalmic imaging features were reviewed by retina specialists for each patient in both eyes.

Posterior Corneal Asphericity and the Refractive Outcome after Combined Phacovitrectomy.

Background: We assessed the correlation of posterior corneal asphericity and the refractive prediction error of the SRK-T and Barrett II Universal formulas for eyes following phacovitrectomy with peeling of the internal limiting membrane (ILM).

Patients And Methods: We retrospectively analyzed 41 eyes of 41 patients following a combined phacovitrectomy with ILM peeling. Surgeries were performed by one fellowship-trained vitreoretinal surgeon between 2016 and 2021.

Visual Outcomes after Implantation of Lucidis EDOF IOL.

Purpose: To evaluate the visual performance and clinical outcomes after implantation of Lucidis EDOF IOL following cataract surgery.

Design: In this retrospective study, medical records from all enrolled patients were analyzed, and the following information was extracted retrospectively over 3 months following surgery.

Materials And Methods: We reviewed retrospectively 181 eyes of 98 patients, who underwent cataract surgery with Lucidis extended depth of focus IOL.

Influence of Posterior Corneal Asphericity On Power Calculation Error After Laser In Situ Keratomileusis or Photorefractive Keratectomy for Myopia.

Objectives: To assess the impact of posterior corneal asphericity on postoperative calculation error using the Haigis-L and the Barrett formulas for eyes after laser in situ keratomileusis or photorefractive keratectomy (PRK).

Methods: We assessed the mean absolute error (MAE) of two power calculation formulas, Barrett true-K and Haigis-L formulas, in a retrospective analysis of 34 eyes of 34 patients who underwent cataract surgery. We performed a regression analysis between corneal parameters (anterior and posterior Q values, Kmax, K1, and K2) and the MAE of each formula.

Posterior Corneal Asphericity Effect on Postoperative Astigmatism after EDOF Intraocular Lens Implantation in Cataract Patients.

Aim: To assess the impact of posterior corneal asphericity on postoperative astigmatism.

Methods: We included retrospectively 70 eyes of 70 patients that underwent cataract surgery. We included data of the value, , 1, 2, astigmatism AL, and ACD.

Influence of Posterior Corneal Asphericity on Refractive Error of SRK-T and Barrett Formulas for Lucidis IOL.

Purpose: To evaluate the influence of posterior corneal asphericity on the refractive error using SRK-T and Barrett formulas for the intraocular lens (IOL) power calculation for Lucidis Extended Depth of Focus (EDOF) IOL.

Setting: This study was carried out at a tertiary ophthalmology center in Geneva, Switzerland.

Design: A retrospective study.

Effects of nifedipine on endothelial function, assessed by flow-mediated vasodilatation in pregnant patients.

Objectives: To evaluate the endothelial function, through flow-mediated vasodilation parameters from brachial artery test in women receiving nifedipine for acute tocolysis with threatened preterm delivery.

Methods: In a prospective study in a university-affiliated hospital, each participant served as herself control. We evaluated various parameters of endothelial function in 22 patients between 27 and 33 weeks of gestation with a diagnosis of threatened preterm delivery (TPTD) before and after 48 h of nifedipine treatment.

Local cerebroplacental ratio reference ranges are better predictors for adverse delivery outcomes in normal weight fetuses during pregnancy.

Objective: To evaluate the predictive value of local versus external cerebroplacental ratio (CPR) reference ranges for delivery outcomes in low-risk pregnancies.

Methods: A retrospective analysis of all feto-maternal demographic and biometric data in fetuses with normal estimated fetal weight (EFW) and a CPR examination between the years 2014-2019, in a university medical center. The study group included healthy singleton pregnancies from 32-week gestation, with an examination-to-delivery interval of <31 days.

Third-trimester Reference Ranges for Cerebroplacental Ratio and Pulsatility Index for Middle Cerebral Artery and Umbilical Artery in Normal-growth Singleton Fetuses in the Israeli Population.

Background: The ratio between the fetal umbilical artery pulsatility index (UA-PI) and the middle cerebral artery pulsatility index (MCA-PI) is termed the cerebroplacental ratio (CPR). The CPR represents fetal blood flow redistribution at the early stages of placental insufficiency; moreover, it has predictive value for adverse intrapartum and neonatal outcomes. However, internationally accepted reference ranges for CPR are lacking.

Barbed Versus Conventional Suture for Uterine Repair During Caesarean Section: A Randomized Controlled Study.

Objective: This study sought to compare the short-term outcome of uterine incision repair during a Caesarean section (CS) using a bidirectional knotless barbed suture versus polyglactin suture.

Methods: A randomized controlled trial was conducted at a university hospital. Participants undergoing a CS were randomly assigned to uterine incision closure by bidirectional knotless barbed suture (group A) or polyglactin (group B).

Trends in primeval β-hCG level increment after fresh and frozen-thawed IVF embryo transfer cycles.

Mid-trimester beta-human chorionic gonadotropin (BHCG) levels are considerably higher in pregnancies resulting from frozen embryo transfer (FET) compared with fresh (FRET), leading to a higher false positive rate in aneuploidy screening tests. We aimed to investigate the dynamics of BHCG increment and its predictive value for cycle outcome. A retrospective analysis of FRET and FET cycles.

Is umbilical vein varix associated with changes in cerebroplacental ratio?

We aimed to review a single-center experience in follow-up and management of fetuses with umbilical vein varix (UVV) and to assess the effect of UVV on fetal Doppler parameters. We reviewed retrospectively maternal antenatal records, delivery records, and newborn records to identify cases of UVV. Further, we retrospectively compared 25 fetuses with isolated UVV and available cerebroplacental ratio (CPR) analysis with 75 matched controls.

Safety of nifedipine in threatened preterm labor: Investigation by three-dimensional echocardiography.

Objective: To evaluate atrial and ventricular parameters using real time three-dimensional transthoracic echocardiography (RT3DTTE) in women treated with nifedipine in the early third trimester (III-T) of pregnancy.

Methods: A prospective single-subject design study in a university-affiliated hospital, where each participant served as her own control. We studied 25 pregnant women at a gestational age of 25-33 weeks with TPTL prior to vs 48 hours postnifedipine treatment.