High incidence of femoroacetabular impingement deformity in bi-column acetabular fractures.

Introduction: Dynamic interaction of cam and pincer deformities can result in pathological contact forces in femoroacetabular impingement (FAI) syndrome. Similar deformities were noted during acetabular fracture reconstruction. We hypothesise that the prevalence of FAI deformity is higher in patients sustaining acetabular fractures than in a control group.

Merging cross-border flow optimization techniques for performance maximization.

Both FARCROSS and TRINITY EU research projects aim to increase cross-border electricity flow and regional cooperation. The integration of SmartValve and T-SENTINEL systems offers benefits such as enhancing grid security and reliability, managing thermal constraints, and maximizing utilization of existing infrastructure. The combined system can achieve a more efficient and less costly coordinated network security process, increase cross-border capacities, and promote regional electricity market integration, benefiting the local communities with significant CO2 emissions avoidance and reduced electricity prices.

Right Heart Thrombus in Transit on Point-of-Care Ultrasound: A Rare Finding with Key Management Repercussions.

• Right heart thrombi are associated with high early mortality in PE. • POCUS allows rapid assessment in hemodynamic compromise and suspected PE. • Triple POCUS assessment of the lung, heart, and leg veins may improve PE detection.

Utility of Transbronchial Biopsy in the Immunocompromised Host With New Pulmonary Radiographic Abnormalities.

Objective: To assess how often transbronchial biopsy (TBBx) added unique positive findings apart from other synchronous bronchoscopic sampling techniques including the bronchoalveolar lavage-immunocompromised host (BAL-ICH) panel that justified changes in management in an array of immunocompromised patients with new pulmonary radiographic abnormalities.

Methods: We retrospectively reviewed all bronchoscopies performed at Mayo Clinic Rochester between January 2012 and December 2017; on the basis of the physician's selection of a BAL-ICH panel, we identified 192 immunocompromised patients who underwent bronchoscopy with both a BAL-ICH panel and TBBx. The results of the BAL-ICH panel and TBBx were compared and subsequent management decisions analyzed from clinical notes.

Use radiography rarely, not routinely, for hip hemiarthroplasty.

Purpose: Hip hemiarthroplasty (HA) is a commonly performed operation. A post-operative radiograph forms part of the routine hip fracture pathway, although patients are often mobilised prior to this investigation. This study seeks to provide evidence for a pragmatic clinical change to optimise patient safety and allocate limited resources within the National Health Service (NHS).

A rare case of chemotherapy induced phrenic neuropathy.

Background: While chemotherapeutic agents result in an improvement in both disease-free and overall survival in cancer patients, treatment can result in short and long-term complications. One well-known complication is neuropathy which can result from a number of chemotherapeutic agents. However, chemotherapy-induced phrenic neuropathy is an exceedingly rare phenomenon with few cases reported in the literature.

Novel use of a trabecular metal spacer in the treatment of a long-standing ulnar fracture non-union.

The use of trabecular metal (TM) implants in spine and joint surgery is well documented. However, their use has yet to be reported as an alternative to either allograft or autograft in the management of fracture non-unions. We present our experience in using a TM implant for treating a patient with a long-standing ulnar fracture non-union.

The posterior acetabular wall (PAW): an aid to acetabular orientation at primary THA.

Introduction: Incorrect acetabular component positioning during total hip arthroplasty (THA) may lead to dislocation, impingement, wear and revision. Surgeons commonly use the transverse acetabular ligament (TAL) as a landmark for acetabular component orientation. The posterior acetabular wall (PAW) is a structure easily viewed on plain radiography and its position can help guide acetabular component position.

Huntingtin fragments and SOD1 mutants form soluble oligomers in the cell.

Diffusion coefficients of huntingtin (Htt) fragments and SOD1 mutants expressed in cells were measured using fluorescence correlation spectroscopy. The diffusion mobilities of both non-pathological Htt fragments (25 polyQs) and pathological Htt fragments (103 polyQs) were much slower than expected for monomers suggesting that they oligomerize. The mobility of these fragments was unaffected by duration of expression or by over-expression of Hsp70 and Hsp40.

Hip stability after ligamentum teres resection during surgical dislocation for cam impingement.

Purpose: The purpose of this study was to investigate whether patients who have undergone surgical hip dislocation with excision of the ligamentum teres exhibited symptoms of a Type I ligamentum teres rupture.

Method: A questionnaire was designed to enquire about specific symptoms attributed to Type I injuries (complete rupture) in the literature: gross instability, incomplete reduction, inability to bear weight and mechanical symptoms. 217 consecutive patients were surveyed and 161 patients (75%) returned 168 questionnaires (75%).

Judet osteoperiosteal decortication for treatment of non-union: the Cornwall experience.

Background: The treatment of non union can be challenging with a variety of surgical options available to achieve bone consolidation. Robert Judet first described a method of osteo-periosteal decortication in 1963. He stated that by elevating cortical chips that remain attached to the periosteum and overlying soft tissues surrounding the site of non-union, combined with mechanical support, the bone consolidated.

Hip resurfacing arthroplasty in patients with varus deformity of the femoral neck-shaft angle.

Hip resurfacing arthroplasty (HRA) in patients with a varus deformity of the femoral neck-shaft angle (NSA) is associated with poorer outcomes. Our experience has not reflected this. We examined the Oxford Hip Scores (OHS), Harris Hip Scores (HHS) and outcomes of patients with varus hips against a normal cohort to ascertain any significant difference.

NMR method for measuring carbon-13 isotopic enrichment of metabolites in complex solutions.

Isotope-based methods are commonly used for metabolic flux analysis and metabolite quantification in biological extracts. Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical tool for these studies because NMR can unambiguously identify compounds and accurately measure (13)C enrichment. We have developed a new pulse sequence, isotope-edited total correlation spectroscopy (ITOCSY), that filters two-dimensional (1)H-(1)H NMR spectra from (12)C- and (13)C-containing molecules into separate, quantitatively equivalent spectra.

Non-union following bilateral simultaneos Ganz trochanteric osteotomy.

Between January 2003 and December 2004, 13 patients underwent bilateral resurfacing arthroplasty via a Ganz trochanteric osteotomy. This bilateral group was mobilised fully weight-bearing with crutches. During the same period 139 Ganz trochanteric osteotomies were performed for unilateral hip resurfacing.

Femoroacetabular impingement and classification of the cam deformity: the reference interval in normal hips.

Background And Purpose: Most patients with femoroacetabular impingement (FAI) have a cam deformity, which may be quantified by measuring the alpha angle and anterior offset ratio (AOR). Knowledge of what constitutes a "normal" alpha angle and AOR is limited. We defined the reference intervals of these measurements from normal hips in the general population.

Early failure of the Dual coat Cormet 2000 metal on metal acetabular component.

We report a 10% failure rate for aseptic loosening and overall revision rate of 15% at 5 years mean follow up in 190 patients using the Cormet 2000 Dual coat acetabular component. Between 2001 and 2004, the original Dual coat component was used in our region by 4 experienced arthroplasty surgeons. 142 were used with resurfacing heads.

Open surgery for hip impingement.

Mechanical impingement of the proximal femur against the acetabular rim is now recognized as a common cause of labral tears and degenerative changes in the hip. Open surgery is successful in treating this condition if damage to the articular cartilage surface is minimal.

Metal-on-metal hip resurfacing: the effect of cup position and component size on range of motion to impingement.

The aim of this dry bone study was to determine the range of hip motion to impingement for different hip resurfacing cup positions and component sizes. The maximum angles of hip flexion, extension, abduction, and adduction were calculated from 3-dimensional coordinates for: 1. Cup inclination of 30 degrees , 40 degrees , 50 degrees , 60 degrees , and 70 degrees with fixed anteversion; 2.

Femoral oxygenation during hip resurfacing through the trochanteric flip approach.

Femoral neck fracture is one of the most common complications of hip resurfacing and considered by some to be related to reduced blood flow as a consequence of the surgical approach. We measured oxygen concentration during hip resurfacing through the trochanteric flip approach (n = 15 patients) and compared this approach with previous data for the posterior and anterolateral approaches. With the trochanteric flip the average femoral oxygenation decreased during the procedure to approximately 50% of that at the start, however it recovered to starting level by the end of the procedure.

Clathrin adaptor GGA1 polymerizes clathrin into tubules.

GGAs, a class of monomeric clathrin adaptors, are involved in the sorting of cargo at the trans-Golgi network of eukaryotic cells. They are modular structures consisting of the VHS, the GAT, hinge, and GAE domains, which have been shown to interact directly with cargo, ARF, clathrin, and accessory proteins, respectively. Previous studies have shown that GGAs interact with clathrin both in solution and in the cell, but it has yet been shown whether they assemble clathrin.

Summer dormancy in perennial temperate grasses.

Background And Aims: Dormancy has been extensively studied in plants which experience severe winter conditions but much less so in perennial herbaceous plants that must survive summer drought. This paper reviews the current knowledge on summer dormancy in both native and cultivated perennial temperate grasses originating from the Mediterranean Basin, and presents a unified terminology to describe this trait.

Scope: Under severe drought, it is difficult to separate the responses by which plants avoid and tolerate dehydration from those associated with the expression of summer dormancy.

Acetabular reconstruction in revision hip surgery using femoral head block allograft.

This prospective study analyzed the clinical and radiological results of 140 consecutive cases of acetabular revision using large frozen femoral head allografts and cemented all-polyethylene acetabular components. Mean follow-up was 10 years (range: 5-16 years). Thirty patients died, seven were lost to follow-up, and 26 had failed and undergone further surgery.

Acetabular component revision with frozen massive structural pelvic allograft: average 5-year follow-up.

We evaluated the use of a hemipelvic acetabular transplant in 20 revision hip arthroplasties with massive acetabular bone defects. We report 65% good intermediate-term results at a mean follow-up of 5 years (4-10 years). A cemented cup (without a reinforcement ring) was entirely supported by the allograft in all procedures.