Publications by authors named "Mark M Mintun"
Alzheimers Dement
July 2018
Article Synopsis
- - The study examined the prevalence of the APOE ε4 genetic risk factor for Alzheimer's disease (AD) in a group of 3451 individuals with confirmed amyloid β (Aβ) pathology, which had not been consistently used in earlier research.
- - Results showed that APOE ε4 prevalence was 66% in AD-type dementia, 64% in mild cognitive impairment, and 51% in cognitively normal individuals, with a notable decrease in prevalence as age increased among those who were cognitively normal or had mild cognitive impairment.
- - The findings indicated that the prevalence of APOE ε4 was higher than previously reported, underscoring significant differences in disease presentation based on age and geographic location, particularly being highest
