Publications by authors named "Mark Lynam"

Article Synopsis
  • - The study focused on oral HPV prevalence in the U.S., noting that oropharyngeal cancer linked to HPV is now more common than cervical cancer, but data on oral HPV in the general population is limited.
  • - Conducted across 43 dental offices from November 2021 to March 2022, the cross-sectional study involved 3,196 participants aged 18 to 60, with samples taken to assess HPV presence and participant behaviors.
  • - Results showed an oral HPV prevalence of 6.6%, with 2.0% for high-risk types and 0.7% for HPV-16; prevalence was notably higher in men, especially those aged 51 to 60.
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Background: Head and neck cancers are increasingly associated with human papillomavirus (HPV) infection. Previous studies of oral HPV indicate considerable heterogeneity across geographic regions and by sex, but studies differ in methodologies used and risk groups included. Understanding the natural history of oral HPV in the general population is important to assess HPV-related disease burden and plan effective prevention programs.

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Background: Ulcerative colitis (UC) is a life time disease and issues with therapy may impact on patient satisfaction and treatment preferences.

Aims: To assess disease and treatment perception gaps from patients' and physicians' perspectives in UC patients.

Methods: Adult patients with moderate-to-severe UC (Mayo score ≥6) naïve to biologic therapy were enrolled in a European, observational, cross-sectional, retrospective study.

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Background: Treatment of ulcerative colitis (UC) is aimed at maintaining corticosteroid-free remission and improving quality of life (QoL).

Aim: Assess patients' perception of disease burden and unmet clinical needs in moderate/severe UC patients.

Methods: Adults surgery-free conventionally treated patients with Mayo score ≥6 were enrolled in an observational, cross-sectional, retrospective study in 11 European countries.

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