Synopsis of recent research by authors named "Mark L C Khoo"
- Mark L C Khoo's research predominantly focuses on thyroid carcinoma and salivary gland tumors, with a significant emphasis on using fine needle aspiration cytology (FNAC) and frozen section histopathology to improve diagnostic accuracy and influence management outcomes for patients with these malignancies
- A key finding from his studies indicates a correlation between the overexpression of cyclin D1 and underexpression of p27/Kip with lymph node metastases in papillary thyroid carcinoma, suggesting these markers may serve as predictive factors for aggressive disease
- Khoo also highlights the importance of recognizing calcifications in thyroid nodules, proposing that their presence may indicate a higher risk for malignancy, contrary to the common dismissal of these findings as incidental through a review conducted at a tertiary referral center
