Publications by authors named "Mark Joseph M Espino"

Article Synopsis
  • *This study examined brain samples from 70 rabid dogs, finding high presence of Negri bodies in the hippocampus (87.14%) and cerebrum (70%), with distinct characteristics in those regions compared to the thalamus and brainstem.
  • *The research highlighted that detecting Negri bodies in the hippocampus and cerebral cortex can aid in rabies diagnosis, while immunohistochemistry showed high sensitivity for identifying rabies virus antigens in all brain regions studied.
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Snail control to complement mass drug administration is being promoted by the World Health Organization for schistosomiasis control. , the snail intermediate host of in the Philippines, has a very focal distribution; thus, scrutinizing baseline data and parameters affecting this distribution is very crucial. In this study in Gonzaga, Cagayan, Philippines, snail habitats were surveyed, and the various factors affecting the existence of the snails were determined.

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Expansion of the use of lateral flow devices (LFD) for animal rabies diagnosis can help mitigate the widespread underreporting of rabies. However, this has been hindered by the limited number and small sample size of previous studies. To overcome this limitation, we conducted a multicenter study with a larger sample size to assess the diagnostic accuracy of the ADTEC LFD for postmortem rabies diagnosis in animals.

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The rabies virus is one of the most neurotropic of all viruses infecting mammals. During the terminal phases of infection, the virus spreads to peripheral tissues, including the skin. The external skin of the nose, called the nasal planum, is a sensory organ where numerous nerve bundles and terminal nerves are distributed.

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