Publications by authors named "Mark J Penny"
Article Synopsis
- - A 73-year-old woman with acromegaly developed interstitial nephritis likely caused by oxalate nephropathy, after starting treatment with pasireotide, a medication known to affect pancreatic function and insulin secretion.
- - Despite the treatment improving her IGF-1 levels, the patient experienced gastrointestinal symptoms and acute kidney injury, leading to a kidney biopsy that confirmed acute-on-chronic interstitial nephritis with oxalate crystals present.
- - Following the withdrawal of pasireotide and treatment with glucocorticoids, her kidney function improved significantly over the next few months.
Monofluorinated di- and tetrahydropyrans via Prins-type cyclisations.
Chem Commun (Camb)
August 2006
The synthesis of a range of fluorinated heterocycles is described via a Lewis acid-mediated Prins-type cyclisation.
View Article and Find Full Text PDFA radical-based approach facilitates the highly stereocontrolled functionalisation of beta-amino alcohols, opening up a new, generally applicable methodology for the preparation of quaternary alpha-amino acids.
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