Case management for acquired brain injury: a systematic review of the evidence base.

Background: Brain Injury Case management involves coordinating and organizing services and systems around people with acquired brain injuries' and their families. This review aimed to answer the question: What is the current available evidence for the use of case management in supporting survivors of ABI?

Methods: Searches were conducted in seven databases (Medline (all), CINAHL, Embase, PsychInfo, Scopus, Web of Science, and PubMed), using a search strategy based on key terms: 'case management' and 'brain injury.' Quality of studies was assessed by the Mixed Methods Assessment Tool (MMAT), and the Joanna Briggs Institute (JBI) checklists.

Developing the 'Life Threads' approach to support families after traumatic brain injury in UK community settings: protocol for a qualitative prefeasibility study.

Introduction: Traumatic brain injury (TBI) brings about inevitable and significant changes for family members. Mental health effects for family members are well documented but there are significant gaps in support options across services. Here, we describe our protocol for a study that seeks to investigate the potential for a narrative, creative approach, the 'Life Threads' approach, as a low intensity, accessible means of support that can be applied across service contexts.

Stakeholder views on cognitive communication assessment and intervention for a person living independently in the community with severe traumatic brain injury.

Background: Cognitive communication disorder (CCD) following traumatic brain injury (TBI) is well documented and these communication problems impede successful re-integration into community living. While there is growing evidence for intervention to both detect and treat the impact of these deficits across the rehabilitation continuum, there are barriers to accessing services. Cognitive communication impairments may be missed because the person can talk, and this may mask the subtle but debilitating impact of a CCD.

Experiences of individuals with acquired brain injury and their families interacting with community services: a systematic scoping review.

Purpose: This scoping review aims to (1) synthesise the research findings on the experiences of individuals with acquired brain injuries, and their families, when interacting with, or accessing, community-based services and (2) identify where gaps in service provision may exist and their cause.

Methods: A systematic search strategy was employed across multiple databases to identify all studies relating to the experiences of individuals with acquired brain injuries and their families when interacting with, or accessing, community-based services. Inclusion was assessed by at least two reviewers at each stage and data extraction was completed by one researcher and validity checked by another.

Routine use of immunosuppressants is associated with mortality in hospitalised patients with COVID-19.

Background: Whilst there is literature on the impact of SARS viruses in the severely immunosuppressed, less is known about the link between routine immunosuppressant use and outcome in COVID-19. Consequently, guidelines on their use vary depending on specific patient populations.

Methods: The study population was drawn from the COPE Study (COVID-19 in Older People), a multicentre observational cohort study, across the UK and Italy.

The influence of ACE inhibitors and ARBs on hospital length of stay and survival in people with COVID-19.

Objective: During the COVID-19 pandemic the continuation or cessation of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARBs) has been contentious. Mechanisms have been proposed for both beneficial and detrimental effects. Recent studies have focused on mortality with no literature having examined length of hospital stay.

The effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort study.

Background: The COVID-19 pandemic has placed unprecedented strain on health-care systems. Frailty is being used in clinical decision making for patients with COVID-19, yet the prevalence and effect of frailty in people with COVID-19 is not known. In the COVID-19 in Older PEople (COPE) study we aimed to establish the prevalence of frailty in patients with COVID-19 who were admitted to hospital and investigate its association with mortality and duration of hospital stay.

Accepting what we do not know: A need to improve professional understanding of brain Injury in the UK.

Acquired brain injury (ABI) can lead to life-long changes and disability. The complex and extensive nature of behavioural, cognitive, executive, physical and psychological difficulties mean ABI survivors and their families may come into contact with a range of health and social care services as part of their long-term care. This study aimed to understand the ABI knowledge base of professionals across a range of organisations within the UK, and to identify areas for improvement.

The inter-relationship between acquired brain injury, substance use and homelessness; the impact of adverse childhood experiences: an interpretative phenomenological analysis study.

Purpose: Acquired Brain Injuries, caused by a range of illnesses and injuries, can lead to long-term difficulties for individuals; mental health problems, cognitive and executive impairment and psychosocial problems including relationship breakdown, substance abuse and potentially homelessness. The study aimed to seek and gain a more definitive understanding of the inter-relationship of Acquired Brain Injury, substance abuse and homelessness by identifying key themes associated with the inter-relationship between these variables.

Materials And Methods: The study recruited eight participants through homeless organisations and treatment centres.

Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine.

Streptococcus pneumoniae is the main bacterial pathogen involved in pneumonia. Pneumococcal acquisition and colonization density is probably affected by viral co-infections, the local microbiome composition and mucosal immunity. Here, we report the interactions between live-attenuated influenza vaccine (LAIV), successive pneumococcal challenge, and the healthy adult nasal microbiota and mucosal immunity using an experimental human challenge model.

Experiences of challenges and support among family members of people with acquired brain injury: a qualitative study in the UK.

Primary Objective: Family members (FM) are affected by the impact of an Acquired Brain Injury (ABI) upon their relatives and play an important role in rehabilitation and long-term support. This study explores how families are affected and integrates their views on the formal/informal support received as a consequence of ABI.

Research Design: A qualitative research design was employed to capture the lived experience of FM of people with ABI.

The interrelationship of functional skills in individuals living in the community, following moderate to severe traumatic brain injury.

Objective: The Adaptive Behaviour and Community Competency Scale was used to investigate the interrelationship of 22 basic and instrumental activities of daily living (ADL/IADL) in individuals with moderate to severe traumatic brain injury (TBI). The relationship of self-awareness to task performance was also investigated.

Research Design: Prospective descriptive study.

Inflammation induced by influenza virus impairs human innate immune control of pneumococcus.

Colonization of the upper respiratory tract by pneumococcus is important both as a determinant of disease and for transmission into the population. The immunological mechanisms that contain pneumococcus during colonization are well studied in mice but remain unclear in humans. Loss of this control of pneumococcus following infection with influenza virus is associated with secondary bacterial pneumonia.

Acquired Brain Injury, Parenting, Social Work, and Rehabilitation: Supporting Parents to Support Their Children.

Growing numbers of adults live with the consequences of acquired brain injury (ABI). Those affected frequently require medical input, rehabilitation, and social care. Individuals could suffer from a range of impairments that affect functional abilities.

Acquired Brain Injury, Social Work and the Challenges of Personalisation.

Increasing numbers of adults in the UK are living with acquired brain injury (ABI), with those affected requiring immediate medical care and longer-term rehabilitative and social care. Despite their social needs, limited attention has been paid to people with ABI within the social work literature and their needs are also often overlooked in policy and guidance. As a means of highlighting the challenge that ABI presents to statutory social work, this paper will start by outlining the common characteristics of ABI and consider the (limited) relevant policy guidance.

Factors influencing community case management and care hours for clients with traumatic brain injury living in the UK.

Objective: To investigate the relationship between deficits associated with traumatic brain injury (TBI) and case management (CM) and care/support (CS) in two UK community samples.

Research Design: Prospective descriptive study.

Method: Case managers across the UK and from a single UK CM service contributed client profiles to two data sets (Groups 1 and 2, respectively).

Life care planning and long-term care for individuals with brain injury in the UK.

Introduction: This article explores Life Care Planning and the models of the provision of rehabilitation, case management and care for people with brain-injury in the context of the health and social care systems in the UK.

Background: Life Care Planning for individuals with brain injury is not generally a term recognised or understood in the UK. The authors have worked in the field of rehabilitation, case management and care with this client group for many years and integrated their knowledge of the systems associated with Life Care Planning in the UK.