Publications by authors named "Mark G Pinches"
Toxicol Pathol
December 2014
Article Synopsis
- Recent research aims to identify urinary biomarkers for nephrotoxicity that are more sensitive and specific compared to traditional biomarkers like serum creatinine.
- The study used cisplatin-treated rats to evaluate the relationship between tissue and urinary levels of various biomarkers to assess kidney damage.
- Key findings included that most biomarkers, particularly KIM-1 and OPN, correlated well with urinary measurements and indicated tissue damage, suggesting their potential use in future studies on renal toxicity.
