Publications by authors named "Mark G Kosenko"
Article Synopsis
- An observational study was conducted on patients with early-stage endometrial cancer and atypical endometrial hyperplasia who were seeking to preserve their reproductive functions via organ-preserving treatments.
- The study aimed to analyze gene methylation levels in tissue samples from these patients before treatment, comparing those with good responses to hormonal therapy to those with insufficient responses.
- Results indicated that while all patients with atypical hyperplasia had a complete response to treatment, there were significant differences in gene methylation levels among groups, highlighting varying responses between those with endometrial cancer and the control group; however, the differences in methylation levels were not statistically significant for the complete response group.
Introduction: Experimental studies on animals have demonstrated a higher neuroprotective efficacy of hypercapnic hypoxia compared to normocapnic hypoxia. Respiratory training with hypercapnic hypoxia has shown a positive impact on the functional state of the nervous system in children with cerebral palsy (CP). It can be presumed that the combined effect of moderate hypercapnia and hypoxia will be promising for clinical application within the context of early rehabilitation after ischemic stroke.
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