Publications by authors named "Mark Ebell"
This article summarizes the top 20 research studies of 2023 identified as POEMs (patient-oriented evidence that matters) and the most highly rated guidelines. A large randomized controlled trial found that the time antihypertensive medications are taken has no effect on important outcomes. A fixed-dose approach to statin prescribing is not inferior to a treat-to-target strategy for management of lipid levels.
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- The study aimed to investigate the symptoms, duration, severity, and microbiology of lower respiratory tract infections (LRTI) in outpatients, utilizing a cohort of adults with cough complaints.
- Results indicated that viral infections were associated with less severe symptoms and shorter durations of cough compared to bacterial infections, with an average cough duration of 16.4 days across the cohort.
- The most common detected pathogens included viruses like rhinovirus and influenza, as well as bacteria such as Haemophilus influenzae and Moraxella catarrhalis, with mixed infections showing a higher incidence of severe symptoms.
Introduction: We previously developed a simple risk score with 3 items (age, patient report of dyspnea, and any relevant comorbidity), and in this report validate it in a prospective sample of patients, stratified by vaccination status.
Methods: Data were abstracted from a structured electronic health record of primary care and urgent care 8 patients with COVID-19 in the Lehigh Valley Health Network from 11/21/2021 and 10/31/2022 9 (Omicron variant). Our previously derived risk score was calculated for each of 19,456 patients, 10 and the likelihood of hospitalization was determined.
Background: Antibiotic use remains common for the treatment of lower respiratory tract infections. The objective of this study was to evaluate the impact of antibiotic use on the duration and severity of acute lower respiratory tract infection (LRTI).
Participants: Adult patients presenting to US primary or urgent care sites with a chief complaint of cough and symptoms consistent with LRTI.