Higher levels of cystatin C are associated with worse cognitive function in older adults with chronic kidney disease: the chronic renal insufficiency cohort cognitive study.

Objectives: To determine the association between cognition and levels of cystatin C in persons with chronic kidney disease (CKD).

Design: Prospective observational study.

Setting: Chronic Renal Insufficiency Cohort Cognitive Study.

Central pulse pressure in chronic kidney disease: a chronic renal insufficiency cohort ancillary study.

Central pulse pressure (PP) can be noninvasively derived using the radial artery tonometric methods. Knowledge of central pressure profiles has predicted cardiovascular morbidity and mortality in several populations of patients, particularly those with known coronary artery disease and those receiving dialysis. Few data exist characterizing central pressure profiles in patients with mild-moderate chronic kidney disease who are not on dialysis.

Detection of skin erythema in darkly pigmented skin using multispectral images.

Objective: To develop a technique using a fixed, discrete set of wavelengths that can detect erythema in persons with darkly pigmented skin. The resulting erythema detection approach will then be incorporated into a handheld, point-of-care device that is clinically viable and affordable.

Design: A multispectral imaging system was used to acquire spectral images of induced erythema.

Assessment of an ultrasonic dermal scanner for skin thickness measurements.

The measurement precision of a 20 MHz ultrasound dermal scanning system, Episcan, manufactured by Longport Inc. was investigated for its use in the measurement of skin thickness. Results from measurements of relatively ideal homogeneous, uniformly thick plastic plates indicate that the scanner can accurately measure to depths of 8-34 mm from the surface of the transducer or approximately 18 mm from the surface of the latex probe-cover with a high level of precision, less than 1% of the mean thickness.