Recruitment Strategies and Obstacles During the Zoster Eye Disease Study.

Purpose: The aim of this study was to identify successful recruitment strategies and obstacles reported by principal investigators (PIs) of the Zoster Eye Disease Study (ZEDS).

Methods: A web-based survey was created by a subset of ZEDS PIs and distributed to ZEDS PIs after study enrollment was closed. The survey queried investigators about recruitment strategies and obstacles, use of prophylactic oral antiviral medication, electronic medical records, telemedicine, COVID-19 effect, turnover of research staff, and recruitment outreach to minority and underserved populations.

Strong associations between specific HLA-DQ and HLA-DR alleles and the tubulointerstitial nephritis and uveitis syndrome.

Purpose: To identify genetic markers for the tubulointerstitial nephritis and uveitis (TINU) syndrome by using human leukocyte antigen (HLA) genotyping.

Methods: Eighteen patients who had TINU syndrome were evaluated at three institutions. Typing of class I and II genes was performed by using DNA-based techniques.

Treatment of conjunctival squamous cell carcinoma with topical cidofovir.

Purpose: To describe a case of conjunctival squamous cell carcinoma in situ that was successfully treated with adjunctive topical cidofovir.

Design: Interventional case report.

Methods: A 52-year-old woman presented with a diagnosis of diffuse conjunctival papillomatosis in the right eye.