Real-time tumor tracking in the lung using an electromagnetic tracking system.

Purpose: To describe the first use of the commercially available Calypso 4D Localization System in the lung.

Methods And Materials: Under an institutional review board-approved protocol and an investigational device exemption from the US Food and Drug Administration, the Calypso system was used with nonclinical methods to acquire real-time 4-dimensional lung tumor tracks for 7 lung cancer patients. The aims of the study were to investigate (1) the potential for bronchoscopic implantation; (2) the stability of smooth-surface beacon transponders (transponders) after implantation; and (3) the ability to acquire tracking information within the lung.

Does this patient have influenza?

Context: Influenza vaccination lowers, but does not eliminate, the risk of influenza. Making a reliable, rapid clinical diagnosis is essential to appropriate patient management that may be especially important during shortages of antiviral agents caused by high demand.

Objectives: To systematically review the precision and accuracy of symptoms and signs of influenza.