Publications by authors named "Marjorie Ganner"
Article Synopsis
- * Lineage M1 has emerged as the primary cause of these invasive infections, showing reduced genetic diversity and fewer mutations compared to earlier M1 strains that date back to 2008.
- * Despite being undetected before, M1 clades rapidly spread across the UK after the COVID-19 pandemic, suggesting that waning immunity and specific genetic traits enhance their ability to cause epidemics and survive population bottlenecks.
Background: The morbidity and mortality associated with Panton-Valentine leucocidin (PVL)-positive Staphylococcus aureus suggest that this toxin is a key marker of disease severity. Nevertheless, the importance of PVL in the pathogenesis of primary bacteraemia caused by S. aureus is uncertain.
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