Publications by authors named "Marjolein A B Bakker van der Jagt"
A Prospective Single-Arm Phase 2 Study of Stereotactic Magnetic Resonance Guided Adaptive Radiation Therapy for Prostate Cancer: Early Toxicity Results.
Anna M E Bruynzeel Shyama U Tetar Swie S Oei Suresh Senan Cornelis J A Haasbeek Marjolein A B Bakker van der Jagt
Int J Radiat Oncol Biol Phys
December 2019
Article Synopsis
- Stereotactic body radiation therapy (SBRT) is increasingly used for localized prostate cancer, but there are concerns about potential gastrointestinal (GI) and genitourinary (GU) toxicities from intensive radiation methods.
- A phase 2 study involving 101 patients aimed to assess early GI and GU toxicity after administering SBRT using Magnetic Resonance guided Radiation Therapy (MRgRT), which allows for more precise treatment delivery and adaptive planning.
- The results showed that early GU toxicity was at 23.8% and GI toxicity was at 5%, with no instances of grade 3 GI toxicity, highlighting a lower incidence of early adverse effects due to the precision offered by MRgRT.