Publications by authors named "Marjolaine Mailhot"
Article Synopsis
- - Cystic fibrosis-related diabetes (CFRD) is a common issue in cystic fibrosis patients, characterized by normal fasting blood glucose but problematic post-meal glucose levels, which can worsen health outcomes.
- - This study aimed to test whether soluble fiber supplements could lower post-prandial glucose levels in cystic fibrosis patients with glucose intolerance or CFRD through a double-blind crossover approach with three different interventions.
- - Results showed that fiber supplementation did not improve post-prandial glucose control; however, all participants had lower blood glucose levels after lunch compared to breakfast, despite consuming more carbohydrates.
Article Synopsis
- Cystic fibrosis patients frequently experience fat-soluble vitamin deficiencies, particularly vitamin K, which can impact their respiratory and endocrine health.* -
- A study found that 66% of adult CF patients had suboptimal vitamin K levels, linked to higher risk of colonization by bacteria, lower BMI, and pancreatic insufficiency.* -
- Patients with low vitamin K levels also showed reduced insulin secretion, suggesting a significant connection between vitamin K deficiency and overall health in CF, warranting further research.*
Article Synopsis
- A study from 1992 showed that respiratory function and nutrition decline before developing cystic fibrosis-related diabetes (CFRD), prompting a re-evaluation of these findings.
- Researchers analyzed data from a 6-year prospective study on cystic fibrosis patients, comparing those who later developed CFRD to those who remained normoglycemic, focusing on their nutritional status and lung function over time.
- The results indicated that CFRD onset is not preceded by deterioration in BMI or lung function, suggesting that low BMI and respiratory issues are more linked to pancreatic insufficiency rather than a pre-diabetic condition.
Background: For patients with cystic fibrosis (CF), maintaining a normal BMI is associated with better pulmonary function (FEV1) and survival. Given therapy improvements, some patients are now overweight, obese or present rapid weight gain. However, the impact of being overweight on clinical outcomes (e.
View Article and Find Full Text PDFBackground & Aims: Vitamin D (Vit D) deficiency in cystic fibrosis (CF) is partially secondary to exocrine pancreatic insufficiency. Our aim was to establish a Vit D supplementation protocol that will increase 25(OH)D to the recommended level (30 ng/mL).
Methods: Retrospective study of 200 patients (≥18 years) conducted from February 2007 to June 2014 at the CF clinic of the Centre Hospitalier de l'Université de Montréal.
Background: Zinc status has been previously documented in cystic fibrosis (CF) infants, children and adolescents. However, despite the increasing life expectancy observed in CF populations, data regarding zinc status of CF adults are surprisingly lacking. The objectives of this study were to (1) characterize zinc status and (2) explore associations between zinc status and clinical outcomes of CF adult patients.
View Article and Find Full Text PDFThere is no guideline regarding the concomitant or distant administration of sevelamer and calcium carbonate. Our aim was to determine whether serum phosphate varied when sevelamer and calcium carbonate were administered concomitantly in comparison to administration at separate meals. Fourteen chronic hemodialysis patients were enrolled in this cross-over, randomized trial.
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