Validation of pathogen reduced plasmas from maxi-pools combined with fast thawing.

Objectives: Fast thawing for emergency situations and reduction of plasma wastage.

Background: Evaluation of plasma units, pooled and pathogen reduced (PR) in "maxi-pools" with amotosalen and UVA light, and fast thawing.

Methods/materials: Per replicate, 10 WB-derived leukocyte depleted plasma units were frozen within 24 h at ≤ -25°C and stored for 7 days.

[Awareness of risk for transfusion reactions important for appropriate treatment].

Blood transfusions are still associated with risk for adverse events despite a long tradition for improvement of safety. The incidence of reactions is reported to be about 78/100 000 transfusions with 25 % of these being serious. Some types of reactions are rare and may thus be unrecognised.

Patterns of blood use in Sweden from 2008 to 2017: A nationwide cohort study.

Background: Transfusion patterns in Sweden have not been characterized on a nationwide level.

Study Design And Methods: We conducted a nationwide descriptive cohort study in Sweden from 2008 to 2017. Data on blood donors, donations, component manufacture, transfusions, and transfused patients were extracted from Swedish portion of the Scandinavian Donations and Transfusions (SCANDAT3-S) database.

Analysis of the adequate size of a cord blood bank and comparison of HLA haplotype distributions between four populations.

The number of units and especially the number of different HLA haplotypes present in a cord blood (CB) bank is a crucial determinant of its usefulness. We generated data relevant to the development of our national CB in Finland. The HLA haplotype distribution was examined between specific populations.

Month of birth is associated with multiple sclerosis but not with HLA-DR15 in Finland.

Background: Spring birth has been found to be associated with increase in the risk of MS. However, this effect is reportedly found particularly in HLA-DR15 positive patients.

Objective: Examine the month of birth (MOB) effect in Finnish MS patients and its association with HLA-DR15.

The aging population poses a global challenge for blood services.

Background: The Finnish transfusion registry data suggest some alarming signals and future challenges that are likely to be faced by transfusion services as populations continue to age.

Study Design And Methods: Computerized data collection was performed on all potentially transfused patients in Finland, thus covering approximately 70% of all blood usage. We simulated the red blood cell (RBC) usage according to the Finnish practice on different age groups but the population demographics from other countries.

Bartonella spp. seroprevalence in healthy Swedish blood donors.

Serum samples were collected from healthy blood donors in 5 regions in Sweden in 1999, i.e. from the local Blood Centres (collecting facilities) in Boden, Jönköping, Lund, Skövde, and Uppsala.