Publications by authors named "Mariusz Gawrych"

Biogeographical ancestry analysis is valuable in forensic investigations, especially in missing person cases or crimes without eyewitnesses, as it helps to infer geographic origins from genetic markers. This approach enhances forensic efforts by providing essential clues for identifying individuals with limited direct evidence. Slavic-speaking populations are poorly distinguishable based on human genome variability.

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Article Synopsis
  • Lupus erythematosus (LE) is an autoimmune disease influenced by genetic and environmental factors, with a focus on the C-C motif chemokine receptor 5 gene's role in its development.
  • The study aimed to explore the link between a specific 32bp deletion in the rs333 gene and the occurrence of LE and its symptoms.
  • Results showed that the deletion was more common in healthy individuals than those with discoid lupus erythematosus, suggesting it might serve as a protective factor against DLE but not systemic lupus erythematosus, indicating that larger studies are needed for confirmation.
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Introduction: Toll-like receptor 7 (TLR7) is an important molecule involved in the development of autoimmunity and the response to different pathogens. Several polymorphisms within the gene were previously found to be associated with systemic lupus erythematosus (SLE). However, none of those studies investigated the promoter flanking variants rs1634318 and rs1616583.

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Introduction: Many studies have shown that some SNPs might be a risk factor for systemic lupus erythematosus (SLE), but little is known about potential susceptibility loci of the skin types of the disease. Discoid lupus erythematosus (DLE) is the most common form of the cutaneous lupus erythematosus. Nevertheless, a genetic contribution to DLE is not fully recognized.

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Low-level laser (light) therapy (LLLT) has been applied recently to body contouring. However the mechanism of LLLT-induced reduction of subcutaneous adipose tissue thickness has not been elucidated and proposed hypotheses are highly controversial. Non-obese volunteers were subject to 650nm LLLT therapy.

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