Publications by authors named "Maritza Londono Berrio"
Article Synopsis
- Tumor organoids are 3D structures made from patient cells that replicate the characteristics of actual tumors, making them useful for testing cancer treatments.
- The literature lacks comprehensive information on the development, properties, and identification tools for these organoids, indicating a need for standardization and better understanding.
- As interest in tumor organoids grows, they are being increasingly used to evaluate drugs for various cancers, with the potential to enhance alignment between laboratory results and patient responses in clinical practice.
Drug nanoencapsulation increases the availability, pharmacokinetics, and concentration efficiency for therapeutic regimes. Azobenzene light-responsive molecules experience a hydrophobicity change from a polar to an apolar tendency by photoisomerization upon UV irradiation. Polymeric photoresponse nanoparticles (PPNPs) based on azobenzene compounds and biopolymers such as chitosan derivatives show prospects of photodelivering drugs into cells with accelerated kinetics, enhancing their therapeutic effect.
View Article and Find Full Text PDFGlobal demand for energy is rapidly increasing, and resources for the production of petroleum-based fuels are running out. For this, renewable fuels like biodiesel and hydrotreated vegetable oil biofuel are considered important alternatives to replace such fuels. In this study, we evaluated the in vitro genotoxicity effect on HepG2 cells of organic material extracted from particulate matter emissions of an engine fueled with conventional diesel or mixtures of diesel with 10% of biomass.
View Article and Find Full Text PDFArticle Synopsis
- Nanoencapsulation is a modern technology that protects and enhances the delivery of drugs at the nanoscale, improving their effectiveness and reducing side effects.
- A new photoresponsive polymeric nanocarrier was developed, using modified chitosan, to deliver drugs specifically to target cells under UV light.
- This approach allows for controlled and accelerated release of the drug inside cells, which could significantly improve therapeutic outcomes.