Spectroscopic, crystallographic, and Hirshfeld surface characterization of nine-membered-ring-containing 9-meth-oxy-3,4,5,6-tetra-hydro-1-benzo[]azonine-2,7-dione and its parent tetra-hydro-car-ba-zole.

9-Meth-oxy-3,4,5,6-tetra-hydro-1-benzo[]azonine-2,7-dione, CHNO, (I), and 6-meth-oxy-1,2,3,4-tetra-hydro-car-ba-zole, CHNO, (II), represent the structures of a benzoazonine that contains a nine-membered ring and its parent tetra-hydro-car-ba-zole. The mol-ecules of (I) pack together strong amide N-H⋯O hydrogen bonding and weak C-H⋯O inter-actions, whereas the parent tetra-hydro-car-ba-zole (II) packs with C/N-H⋯π inter-actions, as visualized by Hirshfeld surface characterization.

Increased fibroblast density in actinic cheilitis: association with tryptase-positive mast cells, actinic elastosis and epithelial p53 and COX-2 expression.

Background: Actinic cheilitis (AC) is characterized by epithelial and connective tissue alterations caused by ultraviolet sunlight overexposure known as photodamage. Fibroblasts have been linked to photodamage and tumor progression during skin carcinogenesis; however, their role in early lip carcinogenesis remains unknown. The aim of this study was to assess the density of fibroblasts in AC and normal lip (NL) samples and determine their association with markers of lip photodamage.

Trends in prevalence, awareness, treatment and control of hypertension in urban communities in Chile.

Objectives: To evaluate the changes experienced over 15 years in the prevalence, state of awareness, treatment and control of hypertension, in urban communities of the VIII Region of Chile.

Methodology: In order to ensure an objective analysis in comparison of the indicators, the methodological design used in 1988 was replicated: a representative, non-institutionalized sample, considering age, gender and socio-economic level. Blood pressure was measured using mercury manometers during two visits carried out on different days.

[Reproductive history of women consulting in emergency services in a southern region of Chile].

Background: The occurrence and timing of menstrual and reproductive events such as menarche, regularity of menses, births, maternal breastfeeding and menopause play an important role in a woman's life.

Aim: To study the variability of reproductive live from menarche to menopause in different age groups in Chilean Caucasian and Mapuche aborigine females in a southern location of Chile.

Subjects And Methods: A questionnaire about reproductive history was answered by 502 women consulting in six general emergency rooms of different public hospitals of the 8th region of Chile, between May and September 2002.

[Prevalence of symptoms associated with blood pressure in normal and hypertensive population].

Background: High blood pressure should be symptomless. However, popular knowledge attributes some symptoms such as headache, epistaxis or dizziness to high blood pressure.

Aim: To compare the prevalence of headache, epistaxis, subconjunctival hemorrhages and dizziness in people with normal or high blood pressure.