Publications by authors named "Maritza E Ordonez"
A hypothetical study by using molecular modeling for antioxidant capacity of kojic acid derivatives was performed using quantum chemistry calculations by DFT/B3LYP/6-311++G(3d,2p). Four modification approaches were considered namely simplification, functional modifications, ring regioisomerism, and hydroxylation. Molecular orbitals, single-electron transfers, hydrogen atom transfers, and spin density distributions were used for antioxidant prediction.
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- * Beta-nitrostyrene and its derivatives, particularly 1-nitro-2-phenylethene (NPe), have various biological effects, including anti-inflammatory properties, yet research on their anti-inflammatory potential is limited.
- * The study found that NPe effectively reduced inflammation in both lab and animal tests by lowering levels of the inflammatory cytokine TNF-α and inhibiting specific pathways (NF-κB and ERK1/2), showing promise similar to the known anti-inflammatory drug dexamethasone.