Publications by authors named "Marita A Cardoso"
The role of Reactive Oxygen Species (ROS) on biological media has been shifting over the years, as the knowledge on the complex mechanism that lies in underneath their production and overall results has been growing. It has been known for some time that these species are associated with a number of health conditions. However, they also participate in the immunoactivation cascade process, and can have an active role in theranostics.
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- - Three types of carbon dots (Cdots) were created using carbohydrates and then modified with polyethylene glycol (PEG) and folic acid (FA) to enhance their biological compatibility and sensing capabilities.
- - The modified carbon dots (CdotsPEGFA and CdotsFA) were tested as sensors for nitric oxide radicals (NO·) and showed significant quenching of fluorescence in the presence of this radical, indicating a strong interaction with a 1:1 stoichiometry.
- - Detection limits and sensitivity for the CdotsFA and CdotsPEGFA were found to be suitable for biological applications, with values that are comparable to other nanosensors used for NO· detection.
Amine-functionalized bridged silsesquioxanes (BSs) were synthesized from bis[(3-trimethoxysilyl)propyl] amine via a solvent-mediated route. BS-1 and BS-2 were obtained at neutral pH with sub- and stoichiometric amounts of water, respectively, and high tetrahydrofuran content. BS-3 was prepared with hyperstoichiometric water concentration, high tetrahydrofuran content, and hydrochloric acid.
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